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  • Ezetimibe blocks Toxoplasma gondii-, Neospora caninum- and Besnoitia besnoiti-tachyzoite infectivity and replication in primary bovine endothelial host cells

    Authors: Camilo Larrazabal; Liliana M. R. Silva; Carlos Hermosilla; Anja Taubert

    https://doi.org/10.1017/S0031182021000822, 2021

    Published in: Parasitology

    Tags: Ezetimibe; NPC1L1; Toxoplasma gondii; Neospora caninum; Besnoitia besnoiti

  • Extracellular‐Vesicle‐Based Coatings Enhance Bioactivity of Titanium Implants – SurfEV

    Authors: Taisa Nogueira Pansani; Thanh Huyen Phan; Qingyu Lei; Alexey Kondyurin; Bill Kalionis; Wojciech Chrzanowski

    https://doi.org/10.3390/nano11061445, 2021

    Published in: Nanomaterials

    Tags: Extracellular vesicle; titanium; implants; osteointegration; bioactivity; osteoblasts

  • Molecular profiling of the intestinal mucosa and immune cells of the colon by multi‑parametric histological techniques

    Authors: Łukasz Zadka; Karolina Chrabaszcz; Igor Buzalewicz; Ewelina Wiercigroch; Natalia Glatzel‑Plucińska; Łukasz Szleszkowski; Agnieszka Gomułkiewicz; Aleksandra Piotrowska; Krzysztof Kurnol; Piotr Dzięgiel; Tomasz Jurek; Kamilla Malek

    https://doi.org/10.1038/s41598-021-90761-y, 2021

    Published in: Scientific Reports

    Tags: Immunity; CD4+; inflammation; post-mortem interval; tissue fixation

  • Caspase‑8 deficiency induces a switch from TLR3 induced apoptosis to lysosomal cell death in neuroblastoma

    Authors: Marie‑Anaïs Locquet; Gabriel Ichim; Joseph Bisaccia; Aurelie Dutour; Serge Lebecque; Marie Castets; Kathrin Weber

    https://doi.org/10.1038/s41598-021-89793-1, 2021

    Published in: Scientific Reports

    Tags: Extrinsic apoptosis; Caspase-8; Lysosomal permeabilization; programmed cell death

  • Bacteria Single-Cell and Photosensitizer Interaction Revealed by Quantitative Phase Imaging

    Authors: Igor Buzalewicz; Agnieszka Ulatowska-Jarża; Aleksandra Kaczorowska; Marlena Gąsior-Głogowska; Halina Podbielska; Magdalena Karwańska; Alina Wieliczko; Anna K. Matczuk; Katarzyna Kowal; Marta Kopaczyńska

    https://doi.org/10.3390/ijms22105068, 2021

    Published in: International Journal of Molecular Sciences

    Tags: digital holographic tomography; photodynamic inactivation; single-cell bacteria

  • AQP3 Increases Intercellular Cohesion in NSCLC A549 Cell Spheroids through Exploratory Cell Protrusions

    Authors: Sol Min; Chungyoul Choe; Sangho Roh

    https://doi.org/10.3390/ijms22084287, 2021

    Published in: International Journal of Molecular Sciences

    Tags: AQP3; aggregation; collective metastasis; NSCLC; lung cancer

  • Butyrate modulates adipose-derived stem cells isolated from polygenic obese and diabetic mice to drive enhanced immunosuppression

    Authors: Wan-Tseng Hsu; Wei-Jan Huang; Bor-Luen Chiang; Ping-Huei Tseng

    https://doi.org/10.1016/j.jcyt.2021.01.007, 2021

    Published in: ISCT Cytotherapy

    Tags: adipose-derived stem cells; amphiregulin; butyrate; immunomodulation; inducible nitric oxide synthase; metaflammation

  • Stapled Wasp Venom-Derived Oncolytic Peptides with Side Chains Induce Rapid Membrane Lysis and Prolonged Immune Responses in Melanoma

    Authors: Ye Wu; Dong Lu; Yixin Jiang; Jinmei Jin; Sanhong Liu; Lili Chen; Hong Zhang; Yudong Zhou; Hongzhuan Chen; Dale G. Nagle; Xin Luan; Weidong Zhang

    https://doi.org/10.1021/acs.jmedchem.0c02237, 2021

    Published in: Journal of Medicinal Chemistry

    Tags: Immunogenic cell death; cytotoxic; peptide stapling; membrane disruption; breast cancer

  • Application of digital holographic tomography in antitumor effect of cantharides complex on 4T1 breast cancer cells

    Authors: Chen-Wen Lu; Andrey V. Belashov; Anna A. Zhikhoreva; Irina V. Semenova; Chau-Jern Cheng; Li-Yu Su; Chung-Hsin Wu

    https://doi.org/10.1364/AO.416943, 2021

    Published in: Applied Optics

    Tags: Quantitative; Chinese medicine; antitumor; cell death; necrosis; apoptosis

  • SARS-CoV-2 Infection Induces Psoriatic Arthritis Flares and Enthesis Resident Plasmacytoid Dendritic Cell Type-1 Interferon Inhibition by JAK Antagonism Offer Novel Spondyloarthritis Pathogenesis Insights

    Authors: Qiao Zhou; Jayakumar Vadakekolathu; Abdulla Watad; Kassem Sharif; Tobias Russell; Hannah Rowe; Almas Khan; Peter A. Millner; Peter Loughenbury; Abhay Rao; Robert Dunsmuir; Jake Timothy; Giovanni Damiani; Paolo D. M. Pigatto; Piergiorgio Malagoli; Giuseppe Banfi; Yasser M. El-Sherbiny; Cha

    https://doi.org/10.3389/fimmu.2021.635018, 2021

    Published in: Frontiers in Immunology

    Tags: plasmacytoid dendritic cells, interferon alpha, psoriatic arthritis, COVID-19, enthesis