Scientific Publications

Peer-reviewed research using Nanolive imaging

Discover a list of peer-reviewed scientific publications using Nanolive imaging in the fields of drug discovery, cell metabolism, etc.

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  • ATP synthase is essential for high conductance but not low conductance Mitochondrial Permeability Transition

    Authors: M.A. Neginskaya; S.E. Morris; E.V. Pavlov

    https://doi.org/10.1101/2021.11.16.468842, 2022

    Published in: bioRxiv

    Tags: mitochondria; ATP synthase; MTP

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  • Mitochondrial dysfunction and epithelial to mesenchymal transition in head neck cancer cell lines

    Authors: Maria do Carmo Greier; Annette Runge; Jozsef Dudas; Viktoria Pider; Ira-Ida Skvortsova; Dragana Savic; Herbert Riechelmann

    https://doi.org/10.1038/s41598-022-16829-5, 2022

    Published in: Scientific Reports

    Tags: mitochondria; mesenchymal stem cells; head neck cancer

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  • A cold-water polysaccharide-protein complex from Grifola frondosa exhibited antiproliferative activity via mitochondrial apoptotic and Fas/FasL pathways in HepG2 cells

    Authors: Jiahui Zhao; Kaiyue Liang; Hao Zhong; Shizhu Liu; Peilong Sun; Rongjun He

    https://doi.org/10.1016/j.ijbiomac.2022.07.098, 2022

    Published in: International Journal of Biological Macromolecules

    Tags: G. frondosa; Polysaccharide-protein complex; Cold-water extraction; Structural analysis; HepG2 cell inhibitory activity

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  • Laminin Receptor-Mediated Nanoparticle Uptake by Tumor Cells: Interplay of Epigallocatechin Gallate and Magnetic Force at Nano–Bio Interface

    Authors: Sheng-Chieh Hsu; Nian-Ping Wu; Yi-Ching Lu; Yunn-Hwa Ma

    https://doi.org/10.3390/pharmaceutics14081523, 2022

    Published in: Pharmaceutics

    Tags: magnetic nanoparticles; endocytosis; epigallocatechin gallate; 67LR; Akt

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  • Comparative analysis of Radachlorin accumulation, localization, and photobleaching in three cell lines by means of holographic and fluorescence microscopy

    Authors: A.A. Zhikhoreva, A.V. Belashov, T.N. Belyaeva, A.V. Salova, I.K. Litvinov, E.S. Kornilova, I.V. Semenova, O.S. Vasyutinskii

    https://doi.org/10.1016/j.pdpdt.2022.102973, 2022

    Published in: Photodiagnosis and Photodynamic Therapy

    Tags: photodynamic treatment, malignant cells, fluorescent analysis, digital holographic microscopy, phase images

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  • Effects of iron modulation on mesenchymal stem cell-induced drug resistance in estrogen receptor-positive breast cancer

    Authors: Johanna M. Buschhaus, Shrila Rajendran, Brock A. Humphries, Alyssa C. Cutter, Ayşe J. Muñiz, Nicholas G. Ciavattone, Alexander M. Buschhaus, Tatiana Cañeque, Zeribe C. Nwosu, Debashis Sahoo, Avinash S. Bevoor, Yatrik M. Shah, Costas A. Lyssiotis, Pradipta Ghosh, Max S. Wicha, Raphaël Rodriguez, Gary D. Luker

    https://doi.org/10.1038/s41388-022-02385-9, 2022

    Published in: Oncogene

    Tags: breast cancer, stem cells, iron, lysosome, drug resistance, estrogen-targeted therapy

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  • Engineering CpG-ASO-Pt-loaded macrophages (CAP@M) for synergistic chemo-/gene-/immuno-therapy

    Authors: Yuqi Wang, Lingpu Zhang, Yan Liu, Linlin Tang, Juan He, Xiaqing Sun, Muhsin H. Younis, Daxiang Cui, Haihua Xiao, Dong Gao, Xiang-Yang Kong, Weibo Cai, Jie Song

    https://doi.org/10.1002/adhm.202201178, 2022

    Published in: Advanced Healthcare Materials

    Tags: macrophages; antitumor; drug delivery; immunology; immunotherapy; nanomedicine

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  • Feature Application: Smart Lipid Droplet Assay LIVE

    In this application note, we showcase some of the potential uses of the Smart Lipid Droplet Assay (SLDA) including quantifying signs of aging in human skin cells (case study 1); investigating LD dynamics during foam macrophage formation (case study 2); examining LD dry mass dynamics in cancer cells (case study 3), and dissecting the details of LD biogenesis (case study 4).

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  • Technical Note: Smart Lipid Droplet Assay LIVE

    In this Technical Note, we introduce the Smart Lipid Droplet Assay (SLDA) and showcase its output in multiple cell types at varying confluences and across different field of view sizes. We then compare the performance of the SLDA against the fluorescence marker LipidSpot 610, before finishing with a case study where we use the SLDA to quantify how oleic acid (OA) addition changes LD dynamics in pre-adipocyte cells.

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  • Technical Note: Increase biological relevance and simplify your discovery workflow: a case study on cytotoxicity

    In this document, we demonstrate how the CX-A can be used in drug screening. We go through the whole process from image acquisition to data analysis and interpretation. As a case study, we chose to test what extent the art of observing influences the outcome of our experiments; something too often ignored when running live cell experiments. We measured the effects on cell health of four different cell treatments (1) label-free imaging and vehicle; (2) label-free imaging and addition of Mitotracker; (3) fluorescence imaging at low intensity regime and addition of Mitotracker; (4) fluorescence imaging at high intensity regime and addition of Mitotracker, using EA.

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