The 3D Cell Explorer-fluo

Multimodal complete solution: combine high quality non-invasive 4D live cell imaging with epifluorescence for your lab, department, or institute
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3D Cell Explorer-fluo front view

Image: 3D Cell Explorer-fluo

Video: Linking changes in cell morphology to adenovirus infection

Multimodal complete solution: 4D live cell imaging & fluorescence

3D Cell Explorer-fluo

  • Combine fully label-free imaging with correlative epifluorescence to cover a broad array of live cell imaging requirements for your lab, department, or institute
  • Rediscover your living cells through multiplexing: Nanolive datasets contain the simultaneous acquisition of several biological features and organelles – therefore capturing various pathways of cell biology in real-time
  • Extend Live Cell Imaging: image your live cells as long as you need. Limit cell damages caused by fluorescent markers, bleaching and phototoxicity
  • Visualize the invisible: the 3D Cell Explorer-fluo allows you to visualize what would be too small to be captured label-free, such as: proteins, ions (e.g. calcium), viruses, etc

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Quantification Software: EVE Analytics

A solution for unbiased, non-invasive, continuous analysis & quantification in live cell imaging

EVE Analytics for 3D Cell Explorer-fluo

Continuous, multiplexed live cell data, multi-parametric readout

EVE Analytics

EVE Analytics’ user-friendly interface offers a segmentation and analysis solution specific to Nanolive’s content rich data which can deliver meaningful metrics with the highest biological relevance.

Works over long-term experiments where cell confluency changes significantly with no reduction in quality and automatically calculates and delivers numerous live cell metrics in parallel such as dry mass, cell count, cell confluency, cell circularity, cell perimeter, cell area, etc.

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Live T Cell Assay

Label-free AI-assisted segmentation of target cells and T cells in co-culture

The Live T Cell Assay offers a unique opportunity to understand T cell/target cells interactions over time, at both the single-cell and population level. Nanolive’s label-free live cell imaging captures detailed, multiplexed, and texturally rich images of the entire T cell response process: find, bind, stress and kill.

Only Nanolive’s rich images can achieve a clear segmentation of T cells and their targets without using any destructive labels.

Applications

A selected overview of Nanolive’s top applications.

Visualizing mitochondrial trafficking in neurons

Visualizing stress fibers in mesenchymal stem cells

Human bone osteosarcoma epithelial cells (U2OS) cells expressing Histone 2B-GFP and LAMP1-RFP

Disruptive Technology

Visit our technology page here >

The combination of holography and rotational scanning makes Nanolive imaging a revolutionary technology

Nanolive’s technology is unique because it works label-free and reports the 3D refractive index distribution of the cell. The extremely low light power that generates the holograms allows for a total absence of phototoxicity which leads to excellent time resolution.

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Stem Cells Time Lapse and cell organelles a-f.png

Top Image: 10h time-lapse of mESC undergoing mitosis (Refractive Index and 3D visualization). Bottom image: Organelles which are visible label-free with Nanolive technology: a. mitochondria; b. plasma membrane; c. actin fibers; d. lipid droplets; e. lysosomes; f. nuclear envelope, nucleus & nucleoli.

Laser animation gif
Schematic of Nanolive’s light path

Disruptive Technology

Visit our technology page here >

The combination of holography and rotational scanning makes Nanolive imaging a revolutionary technology

Nanolive’s technology is unique because it works label-free and reports the 3D refractive index distribution of the cell. The extremely low light power that generates the holograms allows for a total absence of phototoxicity which leads to excellent time resolution.

Request a quote or demo >

Stem Cells Time Lapse and cell organelles a-f.png

Top Image: 10h time-lapse of mESC undergoing mitosis (Refractive Index and 3D visualization). Bottom image: Organelles that are visible label-free with Nanolive technology: a. mitochondria; b. plasma membrane; c. actin fibers; d. lipid droplets; e. lysosomes; f. nuclear envelope, nucleus & nucleoli.

Laser animation gif
Schematic of Nanolive’s light path

Technical Specifications

Nanolive imaging and analysis platforms

Swiss high-precision imaging and analysis platforms that look instantly inside label-free living cells in 3D

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CX-A

Automated live cell imaging and analysis: a unique walk-away solution for long-term live cell imaging of single cells and cell populations

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3D CELL EXPLORER-fluo

Multimodal Complete Solution: combine high quality non-invasive 4D live cell imaging with fluorescence

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3D Cell Explorer front view

3D CELL EXPLORER

Budget-friendly, easy-to-use, compact solution for high quality non-invasive 4D live cell imaging

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