The 3D Cell Explorer-fluo
Multimodal complete solution: combine high quality non-invasive 4D live cell imaging with epifluorescence for your lab, department, or institute Request a quote or a demo
Image: 3D Cell Explorer-fluo
Video: Linking changes in cell morphology to adenovirus infection
Multimodal complete solution: 4D live cell imaging & fluorescence
3D Cell Explorer-fluo
- Combine fully label-free imaging with correlative epifluorescence to cover a broad array of live cell imaging requirements for your lab, department, or institute
- Rediscover your living cells through multiplexing: Nanolive datasets contain the simultaneous acquisition of several biological features and organelles – therefore capturing various pathways of cell biology in real-time
- Extend Live Cell Imaging: image your live cells as long as you need. Limit cell damages caused by fluorescent markers, bleaching and phototoxicity
- Visualize the invisible: the 3D Cell Explorer-fluo allows you to visualize what would be too small to be captured label-free, such as: proteins, ions (e.g. calcium), viruses, etc
Quantification Software: EVE Analytics
A solution for unbiased, non-invasive, continuous analysis & quantification in live cell imaging
Continuous, multiplexed live cell data, multi-parametric readout
EVE Analytics
EVE Analytics’ user-friendly interface offers a segmentation and analysis solution specific to Nanolive’s content rich data which can deliver meaningful metrics with the highest biological relevance.
Works over long-term experiments where cell confluency changes significantly with no reduction in quality and automatically calculates and delivers numerous live cell metrics in parallel such as dry mass, cell count, cell confluency, cell circularity, cell perimeter, cell area, etc.
Live T Cell Assay
Label-free AI-assisted segmentation of target cells and T cells in co-culture
The Live T Cell Assay offers a unique opportunity to understand T cell/target cells interactions over time, at both the single-cell and population level. Nanolive’s label-free live cell imaging captures detailed, multiplexed, and texturally rich images of the entire T cell response process: find, bind, stress and kill.
Only Nanolive’s rich images can achieve a clear segmentation of T cells and their targets without using any destructive labels.
Applications
A selected overview of Nanolive’s top applications.
Human bone osteosarcoma epithelial cells (U2OS) cells expressing Histone 2B-GFP and LAMP1-RFP
Disruptive Technology
Visit our technology page here >
The combination of holography and rotational scanning makes Nanolive imaging a revolutionary technology
Nanolive’s technology is unique because it works label-free and reports the 3D refractive index distribution of the cell. The extremely low light power that generates the holograms allows for a total absence of phototoxicity which leads to excellent time resolution.
Top Image: 10h time-lapse of mESC undergoing mitosis (Refractive Index and 3D visualization). Bottom image: Organelles which are visible label-free with Nanolive technology: a. mitochondria; b. plasma membrane; c. actin fibers; d. lipid droplets; e. lysosomes; f. nuclear envelope, nucleus & nucleoli.
Disruptive Technology
Visit our technology page here >
The combination of holography and rotational scanning makes Nanolive imaging a revolutionary technology
Nanolive’s technology is unique because it works label-free and reports the 3D refractive index distribution of the cell. The extremely low light power that generates the holograms allows for a total absence of phototoxicity which leads to excellent time resolution.
Top Image: 10h time-lapse of mESC undergoing mitosis (Refractive Index and 3D visualization). Bottom image: Organelles that are visible label-free with Nanolive technology: a. mitochondria; b. plasma membrane; c. actin fibers; d. lipid droplets; e. lysosomes; f. nuclear envelope, nucleus & nucleoli.
Technical Specifications
Nanolive imaging and analysis platforms
Swiss high-precision imaging and analysis platforms that look instantly inside label-free living cells in 3D
CX-A
Automated live cell imaging and analysis: a unique walk-away solution for long-term live cell imaging of single cells and cell populations
3D CELL EXPLORER-fluo
Multimodal Complete Solution: combine high quality non-invasive 4D live cell imaging with fluorescence
3D CELL EXPLORER
Budget-friendly, easy-to-use, compact solution for high quality non-invasive 4D live cell imaging