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Looking inside Nanolive
Nanolive – our story
Nanolive Nanolive delivers breakthrough imaging solutions that combine screening, imaging, and analysis to radically advance how scientists study living cells and provide novel biological insights into the mechanisms of cancer and neurodegenerative diseases. Our...
Feature Application: Calculating kinetic EC50 values from dose-response curves
Introduction Dose-response curves provide important pharmacodynamic properties (efficacy, potency, toxicity, and lethality) for evaluating the performance of candidate drugs in the discovery pipeline. Half maximal effective concentration (EC50) values are a standard...
Webinar: Generating kinetic EC50 values using label-free cytotoxicity assays
In this webinar, Dr. Emma Gibbin-Lameira will show how Nanolive’s label-free, non-invasive imaging can be used to quantify dose-dependent responses of HeLa cells to Chloroquine. Specifically, Dr. Gibbin-Lameira will show that: Dose-dependent experiments can be...
Dissecting the dynamics of Staurosporine-induced cell death
Staurosporine: the protein kinase inhibitor that packed a powerful punch Staurosporine is a powerful antiproliferative agent that inhibits tumor cell growth by inducing cell death via intrinsic apoptotic pathways. Discovered in a soil sample in 1977 by scientists from...
A chronicle through the eras and discoveries of cancer research. How is Nanolive contributing with their innovations?
Cancer A word pernicious enough to make your blood run cold. And one that 19.3 million people have the misfortune to hear every year. Cancer has the unenviable crown of being the leading cause of death worldwide, claiming more than 10 million lives in 2020 alone....
Shining a spotlight on Nanolive research in Belgium
Earlier in the year we published a blogpost highlighting some of the incredible on-going research that Nanolive users in Spain and Portugal are conducting (here), and now it’s Belgium’s turn! Over the next couple of months, we will be updating this page with some of...
18 Scientific publications featuring Nanolive live cell imaging
2021 has been a productive publishing year for owners of Nanolive microscopes, with another 18 since our last update in June (see here). The broad range of topics covered this time highlights the versatility of our technology and the creativity of our clients – from...
Take a tea break with Emma and discover how to quantify cell cytotoxicity in 96 WP format label-free
Our last live virtual event of 2021: a quick scientific tea break with Communication Specialist Dr. Emma Gibbin-Lameira, is now available on demand! Watch as Dr. Gibbin-Lameira presents a powerful cytotoxicity case study showing Nanolive’s unique live cell-based...
Label-free live cell imaging of Toxoplasma gondii infection dynamics in mammalian cells
Toxoplasmosis: public enemy number 1 of pregnant women Toxoplasmosis - infection arising from the obligate intracellular parasite Toxoplasma gondii - is one of the most common diseases in the world. The World Health Organization (WHO) estimates that more than 2...
Nanolive launches the Live T Cell Assay
A Revolution for Immunotherapy Research Nanolive launches the ground-breaking Live T Cell Assay. The Live T Cell Assay is the first multi-parametric, label-free live immuno-oncology assay that is able to measure and characterize in one experiment how T cells find,...
Nanolive earn rave reviews at the Spanish & Portuguese Advanced Optical Microscopy (SPAOM) meeting
In November 2020 Nanolive attended the Spanish & Portuguese Advanced Optical Microscopy (SPAOM) meeting, held remotely from Valencia in Spain. The objective of this annual congress is to keep new researchers in the Iberian Peninsula at the forefront of optical...
Nanolive imaging reveals the behaviour and morphology of human ovarian stromal cells in exquisite detail
What is the function and structure of the ovaries? The ovaries are a vital component of the female reproductive system, playing key roles in hormone production, egg storage, and ovulation. The cells that help perform organ-specific functions such as these, belong to a...
11 Scientific publications featuring Nanolive live cell imaging
April and May have been busy months for our clients with 11 new scientific publications since our last update featuring Nanolive live cell imaging. Most articles were either immuno-oncology & oncology or microbiology & biofilm-related, but there was a sprinkle...
It’s a mitotic catastrophe! Nanolive imaging captures spectacular multinucleation in real time after exposure to Taxol
What is Paclitaxel (Taxol) and how does it work? Paclitaxel, perhaps better known by its brand name Taxol, has long been used as a chemotherapy drug and has been used to treat numerous types of cancer [1]. It is a cytoskeletal drug, which binds to a specific site on...
Webinar: Label-free cytotoxicity assays: do different cell death stimuli show unique signatures in cell metrics?
In this webinar, Dr. Emma Gibbin-Lameira, Communications Specialist at Nanolive reveals how Nanolive imaging can be used to conduct real-time, automated cytotoxicity assays, without the contribution of photo and cytotoxic methodological artefacts. Specifically, she...
Nanolive imaging validates antibody efficacy in the fight against cancer
What is the role of macrophages in the immune response? Macrophages are a type of white blood cell present in our innate immune system. They are specialized effector cells that detect and destroy harmful pathogens (e.g., bacteria or viruses), as well as diseased and...
EVE Analytics for the 3D Cell Explorer-fluo
Rediscover your cells with EVE Analytics' unique, robust, and high-precision segmentation techniqueThanks to EVE Analytics we can now offer precise cell segmentation of living cells for virtually unlimited periods of time. EVE Analytics can segment numerous single...
Investigating the cellular adhesion process in non‐small cell lung cancer cells using Nanolive imaging
Lung cancer: the world's deadliest cancer The World Health Organization (WHO) reports lung cancer as the most common cause of cancer death in 2020. It is estimated to have caused 1.8 million deaths worldwide, 85% of which, were classified as non‐small cell lung...