Nano News
Looking inside Nanolive
Nanolive imaging validates antibody efficacy in the fight against cancer
What is the role of macrophages in the immune response? Macrophages are a type of white blood cell present in our innate immune system. They are specialized effector cells that detect and destroy harmful pathogens (e.g., bacteria or viruses), as well as diseased and...
EVE Analytics for the 3D Cell Explorer-fluo
Continuous, multiplexed live cell data, multi-parametric readout EVE Analytics’ user-friendly interface offers a segmentation and analysis solution specific to Nanolive’s content rich data which can deliver meaningful metrics with the highest biological relevance....
Investigating the cellular adhesion process in non‐small cell lung cancer cells using Nanolive imaging
Lung cancer: the world's deadliest cancer The World Health Organization (WHO) reports lung cancer as the most common cause of cancer death in 2020. It is estimated to have caused 1.8 million deaths worldwide, 85% of which, were classified as non‐small cell lung...
Feature Client: Dr. Joanna Depciuch from the Institute of Nuclear Physics Polish Academy of Sciences (Krakow, Poland)
Dr. Joanna Depciuch, who runs a lab in the Department of Functional Nanomaterials, based at the Institute of Nuclear Physics Polish Academy of Sciences (Krakow, Poland), is the proud owner of a CX-A. Joanna specializes in the synthesis of nanoparticles (NPs),...
Phenotypic Screening, Cell Differentiation & Neuronal Networks: Label-free Analytics Driving Drug Discovery
Nanolive have been working in close collaboration with swiss-based biotech firm Idorsia for several years now. Idorsia, who specialize in the discovery, development, and commercialization of innovative small molecules, have been testing our automated microscope, the...
Nanolive imaging reveals NETosis to play a key role in host-pathogen interactions in Animal African trypanosomosis
Table of content Animal African trypanosomosis (AAT) is a severe threat to animal health AAT is caused by a flagellated euglenozoan protozoa with an unusual indirect life cycle Trypanosomes induce polymorphonuclear neutrophil (PMN) activation as well as neutrophil...
12 Scientific publications, featuring Nanolive live cell imaging
With all the excitement surrounding the launch of our new product, EVE Analytics, we haven’t had time to update you on the great work our clients have been publishing. So here we are, and we are delighted to announce there have been 12 exciting new scientific articles...
Insights into what the Nanolive platform can offer users: a researcher’s perspective
Prof. Christophe Dubois is a self-confessed imaging fanatic, who heads a lab focused on thrombosis at Aix-Marseille University. He is also the proud owner of a CX-A and is one of the first users of EVE Analytics. We caught up with Prof. Dubois to ask him some...
Improve the accuracy of cell metrics using EVE Analytics
Table of contents Objective: cell segmentation in EVE Analytics How are cell metrics impacted? Observations References Objective: cell segmentation in EVE Analytics Nanolive’s label-free technology makes it possible to image cells for long periods of time, at high...
Watch Nanolive’s new webinar: “Increase biological relevance and simplify your discovery workflow”
Nanolive is delighted to announce that you can now access the replay of our latest webinar with the topic "Maximize the biological relevance of your data whilst shortening and simplifying your experimental workflow: EVE Analytics & the CX-A".In this webinar, Dr....
Nanolive imaging suggests that cell-cell fusion could play a key role in the SARS-CoV-2 infection process
Professor Olivier Schwartz heads a 14-person strong laboratory at the Virus and Immunity lab at the prestigious Pasteur Institute in Paris. His lab studies how pathogenic viruses spread and interact with the host immune system. Before 2020, Prof. Schwartz’ research...
Quantifying lipid droplet dynamics in unperturbed cells, label-free
Table of content Introduction: characterization of single cells Background: lipid droplet dynamics 1. Quantifying LD dynamics at the population level 2. Quantifying LD dynamics at the single cell level 3. Quantifying LD dynamics at the individual LD level Conclusions...
Watch Nanolive’s webinar “Label-free quantification of cell metabolism: focus on mitochondria and lipid droplets dynamics”
Nanolive is delighted to announce that you can now watch the replay of our webinar with the topic "Label-free quantification of cell metabolism: focus on mitochondria and lipid droplets dynamics". In this webinar, Dr. Emma Gibbin-Lameira, Communications Specialist at...
Nanolive examines nuclear changes following transcription inhibition, in real time, and label-free
Table of content Transcription factors (TF): a promising therapeutic target for anti-cancer treatment Changes in nuclear structure offer a means of testing the efficiency of transcription inhibitors Nanolive imaging detects major changes in the nucleus, nucleoli and...
Nanolive imaging confirms norepinephrine triggers lipid accumulation in pre-adipocyte cells
Table of content Norepinephrine: a vital modulator of blood pressure, blood sugar, and fat levels in the body Norepinephrine’s mechanism of action: focus on lipolysis Investigating how norepinephrine influences cell morphology using Nanolive label-free live cell...
Can Nanolive cell imaging shed light on the link between valproic acid and steatosis?
Table of content Valproic acid (VPA): anticonvulsant, epigenetic modulator, potential cancer treatment? VPA interferes with metabolite usage often leading to steatosis Investigating changes in cell metabolism using Nanolive label-free, live cell imaging Nanolive...
Label-free live cell imaging of single cells, with a focus on quantifying phenotypic variation in unperturbed cells
Table of content Introduction: characterization of single cells Background: phenotypic variation Experimental approach: how to image single cells using Nanolive live cell imaging solutions? 1. Visualizing phenotypic variability at the population level 2. Analyzing the...
Nanolive’s CX-A competition announcement winner
In early November 2020, we invited pharma and biotech companies to tell us how they would use our CX-A in their research, to solve one of the 10 threats to the human population identified by the World Health Organization in 2019. We were inundated by high quality...