The 3D Cell Explorer
A revolutionary label-free microscope to look instantly inside living cells in 3D Request a quote or demoVideo: Rotating 3D Cell Explorer
Video: Label-free live cell imaging of a Preadipocyte cell with Nanolive imaging
3D Microscope for label-free live cell imaging
3D Cell Explorer
Discover fundamentally new cell behaviours with this compact and budget-friendly solution with the ability to observe and measure dynamics of undisturbed living cells.
- Explore living cells without damaging them: no Stains, no fixation, no bleaching, no phototoxicity
- Obtain new insights with label-free 3D characterization of your living cells in physiological conditions without any bleaching or phototoxicity
- Perform label-free 4D continuous observation of the most sensitive cells from seconds to weeks
- Preserve the intactness of your cells: Nanolive’s 3D Cell Explorer is the world-leader in live cell assays since it delivers the highest cellular information density anywhere available on the market
- Rediscover your living cells through multiplexing: Nanolive datasets contain the simultaneous acquisition of several biological features and organelles– therefore capturing various pathways of cell biology in real-time
Software
STEVE: An intuitive and comprehensive tool to explore live cell data
Image: Software STEVE UI
STEVE is the 3D Cell Explorer’s software counterpart. After the series of holograms has been captured by the hardware, high-resolution images of each plane in the sample are created by computer processing. Improved image resolution is achieved by employing a synthetic aperture and multiple-viewpoint-holographic methods.
STEVE’s intuitive interface controls the microscope, explores live cell data using interactive digital staining and even performs quantitative analysis on cell measurements. STEVE runs smoothly, even during acquisition.
Watch the video to learn more about STEVE.
Applications
A selected overview of Nanolive’s top applications.
Immuno-Oncology
Antibodies being used as a T cell targeting system to wipe out cancer cells.
Disruptive Technology
Visit our technology page here >
The combination of holography and rotational scanning makes Nanolive imaging a revolutionary technology
Nanolive’s technology is unique because it works label-free and reports the 3D refractive index distribution of the cell. The extremely low light power that generates the holograms allows for a total absence of phototoxicity which leads to excellent time resolution.
Top Image: 10h time-lapse of mESC undergoing mitosis (Refractive Index and 3D visualization). Bottom image: Organelles which are visible label-free with Nanolive technology: a. mitochondria; b. plasma membrane; c. actin fibers; d. lipid droplets; e. lysosomes; f. nuclear envelope, nucleus & nucleoli.
Schematic of Nanolive’s light path
Disruptive Technology
Visit our technology page here >
The combination of holography and rotational scanning makes Nanolive imaging a revolutionary technology
Nanolive’s technology is unique because it works label-free and reports the 3D refractive index distribution of the cell. The extremely low light power that generates the holograms allows for a total absence of phototoxicity which leads to excellent time resolution.
Top Image: 10h time-lapse of mESC undergoing mitosis (Refractive Index and 3D visualization). Bottom image: Organelles which are visible label-free with Nanolive technology: a. mitochondria; b. plasma membrane; c. actin fibers; d. lipid droplets; e. lysosomes; f. nuclear envelope, nucleus & nucleoli.
Schematic of Nanolive’s light path
Technical Specifications
Compare Nanolive’s Products
CX-A
Automated live cell imaging: a unique walk-away solution for long-term live cell imaging of single cells and cell populations
3D CELL EXPLORER-fluo
Multimodal Complete Solution: combine high quality non-invasive 4D live cell imaging with fluorescence
3D CELL EXPLORER
Budget-friendly, easy-to-use, compact solution for high quality non-invasive 4D live cell imaging