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  • Endocytosis-mediated mitochondrial transplantation: Transferring normal human astrocytic mitochondria into glioma cells rescues aerobic respiration and enhances radiosensitivity

    Authors: Chao Sun, Xiongxiong Liu, Bing Wang, Zhenhua Wang, Yang Liu, Cuixia Di, Jing Si, Hongyan Li, Qingfeng Wu, Dan Xu, Ji Li, Gang Li, Yupei Wang, Fang Wang and Hong Zhang

    DOI: https://dx.doi.org/10.7150%2Fthno.33100, 2019

    Published in: Theranostics

    Tags: Drug discovery, Immunooncology & Oncology, Mitochondria and Cell Metabolism, cellular respiration, cancer, glycolysis, mitochondria, mitochondrial dysfunction, apoptosis, radiotheraphy, resistance, glioma, endoytosis, aerobic respiration, Warburg effect, radiosensitivity, astrocytes, NAD, NADH

  • Impact of the Food Additive Titanium Dioxide (E171) on Gut Microbiota-Host Interaction

    Authors: Gabriela Pinget, Jian Tan, Bartlomiej Janac, Nadeem O. Kaakoush, Alexandra Sophie Angelatos, John O’Sullivan6, Yen Chin Koay, Frederic Sierro, Joel Davis, Shiva Kamini Divakarla, Dipesh Khanal, Robert J. Moore, Dragana Stanley, Wojciech Chrzanowski and Laurence Macia

    DOI: https://doi.org/10.3389/fnut.2019.00057, 2019

    Published in: frontiers in Nutrition

    Tags: Microbiology and biofilms, host-pathogen interactions, Immunology

  • Besnoitia besnoiti infection alters both endogenous cholesterol de novo synthesis and exogenous LDL uptake in host endothelial cells

    Authors: Liliana M. R. Silva, Dieter Lütjohann, Penny Hamid, Zahady D. Velasquez, Katharina Kerner, Camilo Larrazabal, Klaus Failing, Carlos Hermosilla & Anja Taubert

    DOI: https://doi.org/10.1038/s41598-019-43153-2, 2019

    Published in: Scientific Reports

    Tags: Host-pathogen interactions, Microbiology and biofilms, Besnoitia besnoiti, apicomplexan parasite, infection, lipid droplets, lipids, apicomplexa, cholesterol synthesis, GC-MS, lovastatin, zaragozic, tachyzoite, cholesterol esterification, parasite, lectin, LDL

  • Methamphetamine-induced apoptosis in glial cells examined under markerfree imaging modalities

    Authors: Lianna Y. D’Brant, Habben Desta, Ting Chean Khoo, Anna V. Sharikova, Supriya D. Mahajan, Alexander Khmaladze

    DOI: https://doi.org/10.1117/1.JBO.24.4.046503, 2019

    Published in: Journal of Biomedical Optics

    Tags: Single cell characterization, Drug discovery, Neuroscience, rat, C6 glial cells, methamphetamine, Raman spectroscopy, apoptosis

  • Synthesis of fluorescent molybdenum nanoclusters at ambient temperature and their application in biological imaging

    Authors: Amit Kumar Sharma, Sunil Pandey, Nallin Sharma, Hui-Fen Wu

    DOI: https://doi.org/10.1016/j.msec.2019.01.029, 2019

    Published in: Material Science and Engineering: C

    Tags: Drug discovery, molybdenum nanoclusters, MoNCs, DTT, thiolated dithiothreitol, nanocluster, drug delivery, A549 cells

  • Diagnosing water treatment critical control points for cyanobacterial removal: Exploring benefits of combined microscopy, next-generation sequencing, and cell integrity methods

    Authors: Arash Zamyadi, Caitlin Romanis, Toby Mills, Brett Neilan, Florence Choo, Lucila A., Coral, Deb Gale, Gayle Newcombe, Nick Crosbie, Richard Stuetz, Rita K. Henderson

    DOI: https://doi.org/10.1016/j.watres.2019.01.002, 2018

    Published in: Water Research

    Tags: Microbiology and biofilms, cyanobacteria, water, climate change, public safety, melainabacteria, green algae

  • Antibiofilm Nitric Oxide Releasing Polydopamine Coatings

    Authors: Zahra Sadrearhami, Farah Nabilah Shafiee, Kitty Ka Kit Ho, Naresh Kumar, Marta Krasowska, Anton Blencowe, Edgar H. H. Wong, and Cyrille Boyer

    DOI: https://doi.org/10.1021/acsami.8b16853, 2019

    Published in: American Chemical Society

    Tags: Microbiology and biofilms, polydopamine, antimicrobial coating, nitric oxide, biofilm, multidrug-resistant bacteria, surface modification, nosocomial infections, gram-negative, Pseudomonas aeruginosa, PAO1, PA37, Staphylococcus aureus

  • Degradation of Mitochondria and Oxidative Stress as the Main Mechanism of Toxicity of Pristine Graphene on U87 Glioblastoma Cells and Tumors and HS-5 Cells

    Authors: Sławomir Jaworski, Barbara Strojny, Ewa Sawosz, Mateusz Wierzbicki, Marta Grodzik, Marta Kutwin, Karolina Daniluk and André Chwalibog

    DOI: https://doi.org/10.3390/ijms20030650, 2019

    Published in: International Journal of Molecular Sciences

    Tags: Immunooncology and Oncology, Mitochondria and cell metabolism, Neuroscience, graphene, graphene-based nanomaterials, U87 glioma cells, HS-5 cells, chicken embryo chorioallantoic membrane, pristine, ROS, mitochondrial membrane potential, oxidative stress, apoptosis, necrosis

  • Morphological changes in the ovarian carcinoma cells of Wistar rats induced by chemotherapy with cisplatin and dioxadet

    Authors: A. A. Zhikhoreva, A. V. Belashov, V. G. Bespalov, A. L. Semenov, I. V. Semenova, G. V. Tochilnikov, N. T. Zhilinskaya, and O. S. Vasyutinskii

    DOI: https://doi.org/10.1364/BOE.9.005817, 2019

    Published in: Biomedical Optics Express

    Tags: Drug discovery, Immunooncology and Oncology, anti-cancer therapy, chemotherapeutic agent performance, antitumor tomography, cisplatin, dioxadet, survival rate

     

  • Label free 3D analysis of organelles in living cells by refractive index shows pre-mitotic organelle spinning in mammalian stem cells

    Authors: Patrick A Sandoz, Christopher Tremblay, Sebastien Equis, Sorin Pop, Lisa Pollaro, Yann Cotte, Gisou F van der Goot, Mathieu Frechin

    DOI: https://doi.org/10.1101/407239, 2018

    Published in: bioRxiv

    Tags: Mitochondria and cell metabolism, stem cells, epifluorescence, lipid droplets, mitochondria, endocytosis, organelle spinning