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  • Identification of shared tumor epitopes from endogenous retroviruses inducing high-avidity cytotoxic T cells for cancer immunotherapy

    Authors: Paola Bonaventura; Vincent Alcazer; Virginie Mutez; Laurie Tonon; Juliette Martin; Nicolas Chuvin; Emilie Michel; Rasha E. Boulos; Yann Estornes; Jenny Valladeau-Guilemond; Alain Viari; Qing Wang; Christophe Caux; Stéphane Depil

    https://doi.org/10.1126/sciadv.abj3671, 2022

    Published in: Science Advances

    Tags: adaptive immunity; Human endogenous retroviruses; cancer vaccine; immunotherapy; solid tumors

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  • AlPc/ZnPc-based oncological photodynamic therapy for a selective eradication of leukemic cells from ovarian tissue

    Authors: Saeid Moghassemi; Arezoo Dadashzadeh; Paulo Eduardo Narcizode Souza; Ricardo Bentes Azevedo; Christiani A. Amorim

    https://doi.org/10.1016/j.pdpdt.2021.102555, 2021

    Published in: Photodiagnosis and Photodynamic Therapy

    Tags: Photodynamic therapy; cancer therapy; photosensitizer; ovarian transplantation; leukemia; phthalocyanine; photoimmunotherapy

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  • P2RY12-Inhibitors Reduce Cancer-Associated Thrombosis and Tumor Growth in Pancreatic Cancers

    Authors: Ana Luisa Palacios-Acedo; Soraya Mezouar; Diane Mège; Lydie Crescence; Christophe Dubois; Laurence Panicot-Dubois

    https://doi.org/10.3389/fonc.2021.704945, 2021

    Published in: Frontiers in Oncology

    Tags: pancreatic tumors; thrombosis; clopidogrel; aspirin; P2Y12 receptor

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  • Berberine photo‐activation potentiates cytotoxicity in human astrocytoma cells through apoptosis induction

    Authors: Francesca Carriero; Carolina Martinelli; Fabio Gabriele; Giulia Barbieri; Lisa Zanoletti; Gloria Milanesi; Claudio Casali; Alberto Azzalin; Federico Manai; Mayra Paolillo; Sergio Comincini

    https://doi.org/10.3390/jpm11100942, 2021

    Published in: Journal of Personalized Medicine

    Tags: oxidative stress; phyto-therapy; astrocytoma; glial tumor

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  • Label-free quantitative phase imaging reveals spatial heterogeneity of extracellular vesicles in selected colon disorders

    Authors: Łukasz Zadka; Igor Buzalewicz; Agnieszka Ulatowska-Jarża; Agnieszka Rusak; Maria Kochel; Ireneusz Ceremuga; Piotr Dzięgiel

    https://doi.org/10.1016/j.ajpath.2021.08.005, 2021

    Published in: The American Journal of Pathology

    Tags: digital holographic tomography; extracellular vesicles; Evs; colorectal cancer; ulcerative colitis

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  • Confined migration promotes cancer metastasis through resistance to anoikis and increased invasiveness

    Authors: Deborah Fanfone; Zhi Chong Wu; Jade Mammi; Kevin Berthenet; David Neves; Kathrin Weber; Andrea Halaburkova; François Virard; Félix Bunel; Hector Hernandez-Vargas; Stephen WG Tait; Anca Hennino; Gabriel Ichim

    https://doi.org/10.1101/2021.08.17.456592, 2021

    Published in: bioRxiv

    Tags: metastasis; invasion; anoikis; cancer; motility; evasion; resistance

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  • Controlled release of hydrogen by implantation of magnesium induces P53-mediated tumor cells apoptosis

    Authors: Rui Zan; Hao Wang; Weijie Cai; Jiahua Ni; Bérengère J. C. Luthringer-Feyerabend; Wenhui Wang; Hongzhou Peng; Weiping Ji; Jun Yan; Jiazeng Xia; Yang Song; Xiaonong Zhang

    https://doi.org/10.1016/j.bioactmat.2021.07.026, 2021

    Published in: Bioactive Materials

    Tags: Biodegradable magnesium; hydrogen; tumor apoptosis; underlying mechanism; P53

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  • Significant difference in response of malignant tumor cells of individual patients to photodynamic treatment as revealed by digital holographic microscopy

    Authors: A.A. Zhikhoreva; A.V. Belashov; A.B. Danilova; N.A. Avdonkina; I.A. Baldueva; M.L. Gelfond; T.L. Nekhaeva; I.V. Semenova; O.S. Vasyutinskii

    https://doi.org/10.1016/j.jphotobiol.2021.112235, 2021

    Published in: Journal of Photochemistry and Photobiology B: Biology

    Tags: Digital holographic microscopy; photodynamic treatment; phase images; malignant cells; individual patients

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  • Molecular profiling of the intestinal mucosa and immune cells of the colon by multi‑parametric histological techniques

    Authors: Łukasz Zadka; Karolina Chrabaszcz; Igor Buzalewicz; Ewelina Wiercigroch; Natalia Glatzel‑Plucińska; Łukasz Szleszkowski; Agnieszka Gomułkiewicz; Aleksandra Piotrowska; Krzysztof Kurnol; Piotr Dzięgiel; Tomasz Jurek; Kamilla Malek

    https://doi.org/10.1038/s41598-021-90761-y, 2021

    Published in: Scientific Reports

    Tags: Immunity; CD4+; inflammation; post-mortem interval; tissue fixation

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  • Caspase‑8 deficiency induces a switch from TLR3 induced apoptosis to lysosomal cell death in neuroblastoma

    Authors: Marie‑Anaïs Locquet; Gabriel Ichim; Joseph Bisaccia; Aurelie Dutour; Serge Lebecque; Marie Castets; Kathrin Weber

    https://doi.org/10.1038/s41598-021-89793-1, 2021

    Published in: Scientific Reports

    Tags: Extrinsic apoptosis; Caspase-8; Lysosomal permeabilization; programmed cell death

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