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  • Evaluation of the Anticancer Activity of Calcium Ions Introduced into Human Breast Adenocarcinoma Cells MCF-7/WT and MCF-7/DOX by Electroporation

    Authors: Katarzyna Bieżuńska-Kusiak, Julita Kulbacka, Anna Choromańska, Nina Rembiałkowska, Olga Michel, Jolanta Saczko

    https://doi.org/10.3390/ph16060809, 2023

    Published in: Pharmaceuticals

    Tags: Apoptosis, cell death, breast cancer, calcium electroporation, CaEP

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  • Abrine, an IDO1 inhibitor, suppresses the immune escape and enhances the immunotherapy of anti-PD-1 antibody in hepatocellular carcinoma

    Authors: Xiaowei Liang, Hongwei Gao, Jian Xiao, Shan Han, Jia He, Renyikun Yuan, Shilin Yang and Chun Yao

    https://doi.org/10.3389/fimmu.2023.1185985, 2023

    Published in: Frontiers in Immunology

    Tags: Immunooncology, phagocytosis, fluorescence, IDO1, Abrine, CD47, PD-L1, m6A RNA modification, immune escape, hepatocellular carcinoma, macrophages

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  • Fluoro-labelled sp2-iminoglycolipids with immunomodulatory properties

    Authors: M. Carmen Padilla-Perez; Elena M. Sanchez-Fernandez; Aday Gonzalez-Bakker; Adrian Puerta; Jose M. Padron; Francisco Martín-Loro; Ana I. Arroba; José Manuel Garcia Fernandez; Carmen Ortiz Mellet

    https://doi.org/10.1016/j.ejmech.2023.115390, 2023

    Published in: European Journal of Medicinal Chemistry

    Tags: Cell death, cytotoxicity, apoptosis, necrosis, EVE analytics, dry mass, cancer, oncology

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  • Bioengineered Bacteriophage-Like Nanoparticles as RNAi Therapeutics to Enhance Radiotherapy against Glioblastomas

    Authors: Hao-Han Pang, Chiung-Yin Huang, Pin-Yuan Chen, Nan-Si Li, Ying-Pei Hsu, Jan-Kai Wu, Hsiu-Fang Fan, Kuo-Chen Wei, Hung-Wei Yang

    https://doi.org/10.1021/acsnano.3c01102, 2023

    Published in: ACS Nano

    Tags: Glioblastoma, fluorescence, RNA silencing, gene therapy, drug discovery, endocytosis

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  • An OMA1 redox site controls mitochondrial homeostasis, sarcoma growth, and immunogenicity

    Authors: Richard Miallot, Virginie Millet, Yann Groult, Angelika Modelska, Lydie Crescence, Sandrine Roulland, Sandrine Henri, Bernard Malissen, Nicolas Brouilly, Laurence Panicot-Dubois, Renaud Vincentelli, Gerlind Sulzenbacher, Pascal Finetti, Aurélie Dutour, Jean-Yves Blay, François Bertucci, Franck Galland, Philippe Naquet

    https://doi.org/10.26508/lsa.202201767, 2023

    Published in: Life Science Alliance

    Tags: OMA1, ROS, mitochondrial fission, sarcoma, cancer, immunogenicity, cell death, LCDA

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  • Vorinostat decrease M2 macrophage polarization through ARID1A6488delG/HDAC6/IL-10 signaling pathway in endometriosis-associated ovarian carcinoma

    Authors: Filipczak N, Li X, Saawant GR, Yalamarty SSK, Luther E, Torchilin VP

    https://doi.org/10.1016/j.biopha.2023.114500, 2023

    Published in: Biomedicine & Pharmacotherapy

    Tags: ovarian carcinoma, macrophage polarization, ARID1A, HDAC6, IL-10 and EAOC, cell death, drug discovery, drug response

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  • Multimodal study of CHI3L1 inhibition and its effect on angiogenesis, migration, immune response and refractive index of cellular structures in glioblastoma

    Authors: Rusak, A., Buzalewicz, I., Mrozowska, M., Wiatrak, B., Haczkiewicz-Leśniak, K., Olbromski, M., Kmiecik, A., Krzyżak, E., Pietrowska, A., Moskal, J., Podhorska-Okołów, M., Podbielska, H., & Dzięgiel, P

    https://doi.org/10.1016/j.biopha.2023.114520, 2023

    Published in: Biomedicine & Pharmacotherapy

    Tags: Metastasis, CHI3L1 inhibition, G721-0282, cytoskeleton, migration, actin, U-87 MG, Glioblastoma, Angiogenesis

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  • Erk1/2-Dependent HNSCC Cell Susceptibility to Erastin-Induced Ferroptosis

    Authors: Dragana Savic, Teresa Bernadette Steinbichler, Julia Ingruber, Giulia Negro, Bertram Aschenbrenner, Herbert Riechelmann, Ute Ganswindt, Sergej Skvortsov, József Dudás, Ira-Ida Skvortsova

    https://doi.org/10.3390/cells12020336, 2023

    Published in: Cells

    Tags: HNSCC; erastin; xCT; ERK signaling, ferroptosis

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  • Nanosecond pulsed electric field suppresses growth and reduces multi-drug resistance effect in pancreatic cancer

    Authors: Wojciech Szlasa, Olga Michel, Natalia Sauer, Vitalij Novickij, Damian Lewandowski, Paulina Kasperkiewicz, Mounir Tarek, Jolanta Saczko & Julita Kulbacka

    https://doi.org/10.1038/s41598-023-27605-4, 2023

    Published in: Scientific Reports

    Tags: Exocytosis, microvesicles, microvesicle release, pancreatic cancer, therapy resistance

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  • Photodynamic therapy using OR141-loaded nanovesicles for eradication of leukemic cells from ovarian tissue

    Authors: Saeid Moghassemi, Arezoo Dadashzadeh, Alessandra Camboni, Olivier Feron, Ricardo Bentes Azevedo, Christiani A. Amorim

    https://doi.org/10.1016/j.pdpdt.2022.103139, 2022

    Published in: Photodiagnosis and Photodynamic Therapy

    Tags: Nanoparticle, photodynamic therapy, leukaemia, ovary, fertility preservation, oncology

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