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  • Ovulatory Follicular Fluid Facilitates the Full Transformation Process for the Development of High-Grade Serous Carcinoma

    Authors: Che-Fang Hsu, Pao-Chu Chen, Vaishnavi Seenan, Dah-Ching Ding, Tang-Yuan Chu 

    https://doi.org/10.3390/cancers13030468, 2021

    Published in: Cancers

    Tags: follicular fluid; high-grade serous carcinoma; Fallopian tube; transformation; peritoneal metastasis

  • Oxidative Effects during Irreversible Electroporation of Melanoma Cells – In Vitro Study

    Authors: Wojciech Szlasa, Aleksander Kiełbik, Anna Szewczyk, Nina Rembiałkowska, Vitalij Novickij, Mounir Tarek, Jolanta Saczko, Julita Kulbacka

    https://doi.org/10.3390/molecules26010154, 2021

    Published in: Molecules

    Tags: IRE; oxidative stress; melanoma; permeabilization; membrane alternations

  • Electrochemotherapy with Calcium Chloride and 17-Estradiol Modulated Viability and Apoptosis Pathway in Human Ovarian Cancer

    Authors: Zofia Łapińska, Michał Debiński, Anna Szewczyk, Anna Choromańska, Julita Kulbacka, Jolanta Saczko

    https://doi.org/10.3390/pharmaceutics13010019, 2021

    Published in: Pharmaceutics

    Tags: 17-estradiol; chemotherapy; electrochemotherapy; calcium electroporation; ovarian cancer; MDAH-2774

  • Effects of curcumin based PDT on the viability and the organization of actin in melanotic (A375) and amelanotic melanoma (C32)– in vitro studies

    Authors: Wojciech Szlasa, Stanisław Supplitt, Małgorzata Drąg-Zalesińska, Dawid Przystupski, Krzysztof Kotowski, Anna Szewczyk, Paulina Kasperkiewicz, Jolanta Saczko, Julita Kulbacka

    https://doi.org/10.1016/j.biopha.2020.110883, 2020

    Published in: Biomedicine & Pharmacotherapy

    Tags: curcumin; melanoma; photodynamic therapy; apoptosis; motility

  • Tumor vessel targeted self-assemble nanoparticles for amplification and prediction of the embolization effect in hepatocellular carcinoma

    Authors: Yaqin Wang, Wenting Shang, Hongshan Zhong, Ting Luo, Meng Niu, Ke Xu, Jie Tian

    https://doi.org/10.1021/acsnano.0c04341, 2020

    Published in: ACS Nano

    Tags: coagulation cascade; tumor embolism; vessel density; hepatocellular carcinoma; self-assemble; nanoparticle

  • Apoptosis as the main type of cell death induced by calcium electroporation in rhabdomyosarcoma cells

    Authors: Anna Szewczyk, Jolanta Saczko, Julita Kulbacka

    DOI: https://doi.org/10.1016/j.bioelechem.2020.107592, 2020 

    Published in: Bioelectrochemistry

    Tags: rhabdomyosarcoma, muscle cells, calcium ions, electroporation, caspase 3, apoptosis

  • Bicalutamide Elicits Renal Damage by Causing Mitochondrial Dysfunction via ROS Damage and Upregulation of HIF-1

    Authors: Kuan-Chou Chen, Chang-Rong Chen, Chang-Yu Chen, Kai-Yi Tzou, Chiung-Chi Peng, Robert Y. Peng

    DOI: https://doi.org/10.21873/anticanres.14232, 2020

    Published in: Anticancer Research

    Tags: Oncology and immunooncology, cell metabolism, CX, PC-3 Pca, bicalutamide, Bic, rat mesangial cell, RMC line, mitochondrial dysfunction, HIF-1, oxygen consumption rate, OCR, mitochondria, pgrostate cancer, Pca, cardiovascular damage, renal damage, lactate cehydrogenase, ROS, lysosome, BCL2, caspase-3

  • The antimicrobial peptide tilapia piscidin 3 induces mitochondria-modulated intrinsic apoptosis of osteosarcoma cells

    Authors: Chien-HanYuan, Yi-LingMa, Po-ChangShih, Chao-TingChen, Shu-YuCheng, Chieh-YuPan, Yen-HsuanJean, Yih-MinChu, Sung-ChunLin, Yu-ChengLai, Hsiao-MeiKuo

    DOI: https://doi.org/10.21873/anticanres.14232, 2020

    Published in: Biochemical Pharmacology

    Tags: Immunooncology, oncology, cell metabolism, OS MG63, osteosarcoma, intrinsic apoptosis, TP3, antimicrobial peptide, mitochondria, caspase, blebbing, shrinkage, nuclear fragmentation, chromatin condensation, apoptopodia, ROS, acidification, fission, fusion

  • Feature Application: Characterising cancer cells and their interactions with immune cells

    Authors: Nanolive SA, 2020

    Tags: Immuno-Oncology, immune response, cancer cells, immune cells, disease progression, t-cells, macrophages

  • 3PO as a Selective Inhibitor of 6-Phosphofructo-2-Kinase/Fructose-2,6-Biphosphatase 3 in A375 Human Melanoma Cells

    Authors: Kotowski K, Supplitt S, Wiczew D, Przystupski D, Bartosik W, Saczko J, Rossowska J, Drąg-Zalesińska M, Michel O, Kulbacka J.

    DOI: https://doi.org/10.21873/anticanres.14232, 2020

    Published in: Anticancer Research

    Tags: Immunooncology and oncology, B-raf kinase, 3PO, A375, BRAFV600E, Melanoma, PFKFB3, inhibitor, apoptosis, glucose uptake, cycle arrest