Scientific Publications

Peer-reviewed research using Nanolive imaging

Discover a list of peer-reviewed scientific publications using Nanolive imaging in the fields of drug discovery, cell metabolism, etc.

Filter publications:

Search publications:

Displaying 68 results:

  • Apoptosis as the main type of cell death induced by calcium electroporation in rhabdomyosarcoma cells

    Authors: Anna Szewczyk, Jolanta Saczko, Julita Kulbacka

    DOI:, 2020 

    Published in: Bioelectrochemistry

    Tags: rhabdomyosarcoma, muscle cells, calcium ions, electroporation, caspase 3, apoptosis

  • Bicalutamide Elicits Renal Damage by Causing Mitochondrial Dysfunction via ROS Damage and Upregulation of HIF-1

    Authors: Kuan-Chou Chen, Chang-Rong Chen, Chang-Yu Chen, Kai-Yi Tzou, Chiung-Chi Peng, Robert Y. Peng

    DOI:, 2020

    Published in: Anticancer Research

    Tags: Oncology and immunooncology, cell metabolism, CX, PC-3 Pca, bicalutamide, Bic, rat mesangial cell, RMC line, mitochondrial dysfunction, HIF-1, oxygen consumption rate, OCR, mitochondria, pgrostate cancer, Pca, cardiovascular damage, renal damage, lactate cehydrogenase, ROS, lysosome, BCL2, caspase-3

  • The antimicrobial peptide tilapia piscidin 3 induces mitochondria-modulated intrinsic apoptosis of osteosarcoma cells

    Authors: Chien-HanYuan, Yi-LingMa, Po-ChangShih, Chao-TingChen, Shu-YuCheng, Chieh-YuPan, Yen-HsuanJean, Yih-MinChu, Sung-ChunLin, Yu-ChengLai, Hsiao-MeiKuo

    DOI:, 2020

    Published in: Biochemical Pharmacology

    Tags: Immunooncology, oncology, cell metabolism, OS MG63, osteosarcoma, intrinsic apoptosis, TP3, antimicrobial peptide, mitochondria, caspase, blebbing, shrinkage, nuclear fragmentation, chromatin condensation, apoptopodia, ROS, acidification, fission, fusion

  • Feature Application: Characterising cancer cells and their interactions with immune cells

    In this application note, we begin by examining the interactions between t-cells, dendritic cells, and macrophages (case study 1). We then image t-cells responses to cancer cells (case study 2) and the interactions that occur between t-cells and macrophages (case study 3). We show Nanolive imaging can be used to monitor the response of cancer cells to promising antibody drug conjugate (ADCs) products (case study 4) and novel bispecific antibodies (case studies 5 and 6). Finally, we finish with an example of a drug screen where we describe the phenotypic response of living cells to various kinase inhibitors that have shown promise as anti-cancer treatments (case study 7).

  • 3PO as a Selective Inhibitor of 6-Phosphofructo-2-Kinase/Fructose-2,6-Biphosphatase 3 in A375 Human Melanoma Cells

    Authors: Kotowski K, Supplitt S, Wiczew D, Przystupski D, Bartosik W, Saczko J, Rossowska J, Drąg-Zalesińska M, Michel O, Kulbacka J.

    DOI:, 2020

    Published in: Anticancer Research

    Tags: Immunooncology and oncology, B-raf kinase, 3PO, A375, BRAFV600E, Melanoma, PFKFB3, inhibitor, apoptosis, glucose uptake, cycle arrest

  • TP3, an antimicrobial peptide, inhibits infiltration and motility of glioblastoma cells via modulating the tumor microenvironment

    Authors: Ying-Fa Chen, Po-Chang Shih, Hsiao-Mei Kuo, San-Nan Yang, Yen-You Lin, Wu-Fu Chen, Shiow-Jyu Tzou, Hsin-Tzu Liu and Nan-Fu Chen

    DOI:, 2020

    Published in: Cancer Medicine

    Tags: Immunooncology and oncology, neuroscience, cell mobility, glioblastoma multiforme, infiltration, TP3, tumor microenvironment, adhesion, migration, invasion, invasiveness, filopodia, cell attachment, metastasis, kinase, paxillin, RAS, AKT, ERK, JNK, p38

  • Mesoporous silica nanoparticles functionalized with a dialkoxide diorganotin(IV) compound: In search of more selective systems against cancer cells

    Authors: Diana Díaz-García, Lucia Sommerova, Andrea Martisova, Hana Skoupilova, Sanjiv Prashar, Tomas Vaculovic, Viktor Kanicky, Isabel del Hierro, Roman Hrstka, Santiago Gómez-Ruiz

    DOI:, 2020

    Published in: Microporous and Mesoporous Materials

    Tags: Drug discovery, immunooncology & oncology, 

  • Advancing methods for the analysis of glioblastoma cell motion using quantitative time lapse holographic imaging and cellular tomography

    Authors: Ed Luther, Livia Mendes, Nina Filiczak, Aditi Jhaveri, Lara Milane, Vladimir Torchilin

    DOI:, 2019

    Published in: Society of Photo-Optical Instrumentation Engineers

    Tags: Neuroscience, Immunooncology & Oncology, mitochondria and cell metabolism, glioblastoma, motility, mitochondria, fission, fusion, nanotubes, spheroids

  • Stimuli-sensitive fatty acid-based microparticles for the treatment of lung cancer

    Authors: Katarzyna Reczyńska, Patrycja Marchwica, Dipesh Khanal, Tomasz Borowik, Marek Langner, Elżbieta Pamuła, Wojciech Chrzanowski

    DOI:, 2020

    Published in: Materials and Science Engineering: C

    Tags: Immunooncology & oncology, single cell characterization, drug discovery, lung cancer, cancer therapy, superparamagnetic iron oxide nanoparticles, SPION, solid lipid microparticles, lipid, stimuli-sensitive drug carriers, anticancer drug, paclitaxel, lauric acid, LAU, myrisctic acid, palmitic acid, MYR, PAL, cell viability

  • Neutrophils are mediators of metastatic prostate cancer progression in bone

    Authors: Costanzo-Garvey, D.L., Keeley, T., Case, A.J. et al.

    DOI:, 2020

    Published in: Cancer Immunology, Immunotherapy

    Tags: Immunooncology & oncology, single cell characterization, neutrophils, bone, metastasis, prostate, cancer, STAT5, prostrate cancer, BM-Pca, immunotherapy, Pca, neutrophils, infiltration, apoptosis, cancer growth, cytotoxicity