Webinars

Maximize the biological relevance of your data whilst shortening and simplifying your experimental workflow: EVE Analytics & the CX-A

In this webinar, Dr. Emma Gibbin-Lameira, Communications Specialist at Nanolive:

  • A step-by-step guide to setting-up an experiment and acquiring images with Nanolive’s automated microscope the CX-A, and creating publication-ready data and images using Nanolive’s new quantification solution, EVE Analytics
  • A case study showing how different stress stimuli (cytotoxicity vs. phototoxicity) invoke different types of cell death
  • An in-depth discussion of how cell metrics can be used to quantify different types of cell death

Please register here to view the webinar on-demand

Maximize the biological relevance of your data whilst shortening and simplifying your experimental workflow: EVE Analytics & the CX-A webinar photo

Label-free quantification of cell metabolism: focus on mitochondria and lipid droplets dynamics

In this webinar, Dr. Emma Gibbin-Lameira, Communications Specialist at Nanolive:

  • Shows time-lapse footage of mitochondrial swelling and dysfunction following perturbation.
  • Introduces a cell metric called granularity and discusses whether changes in this measurement could be a signal of stress preceding cell death.
  • Presents a fully quantitative analysis of lipid droplet dynamics in unperturbed cells, starting at the population level and finishing at level of an individual lipid droplet. Correlations between lipid droplet characteristics and other cell morphological traits (e.g. dry mass) are also be featured for the first time.

Please register here to view the webinar on-demand

Image Label-free quantification of cell metabolism: focus on mitochondria and lipid droplets dynamics

Label-free analysis of living cell populations reveals controlled phenotypic variation among single cells

In this webinar, Dr. Emma Gibbin, Communications Specialist at Nanolive:

• Compares the variability of isolated single cells with the variability of single cells in a large population to determine whether heterogeneity is driven by internal or external factors.
• Examines how the variability of individual traits change over time in unperturbed cells.
• Analyzes how cells respond to perturbations in intracellular trafficking and respiration to determine whether targeting different systems induces/reduces the phenotypic variation of single cells in a population.

Please register here to view the webinar on-demand

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Unlocking the mysteries of neurite growth in primary cortical neurones: a quantitative approach to live cell imaging

In this webinar, Dr. Emma Gibbin, Communications Specialist at Nanolive shows how label-free imaging can be used to capture and analyze the fine, dynamic details of neurite growth in unperturbed primary cortical neurons. Specifically, Dr. Gibbin shows:

  • a timeline of the morphological changes undifferentiated primary cortical neurones undergo after exposure to neurite stimulation media
  • high-precision segmentations that show it is possible to separate and quantify the responses (e.g. volume, shape, and dry mass) of neurites from the cell body
  • novel behavioural observations from individual neurons

Please register here to view the webinar on-demand

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Accelerating oncology drug discovery with label-free imaging

In this webinar, Dr. Emma Gibbin, Communications Specialist at Nanolive will discuss the advantages of using label-free live cell imaging in the drug discovery process and show how Nanolive’s automated live cell imaging solution the CX-A, can be used to:

  • observe unique drug-induced phenotypes that fluorescence microscopy cannot capture
  • record dynamic cellular responses to drug perturbations
  • automate in vitro screening studies.

Dr. Gibbin will present novel results from two experimental screens designed to test the phenotypic and morphological responses of pre-adipocyte and cancer cells to 8 inhibitors or modulators of kinase activity.

Please register here to view the webinar on-demand

Characterization of stem cell differentiation dynamics with label-free live cell imaging

In this webinar, Dr. Emma Gibbin, Communications Specialist at Nanolive will:

 

  • discuss the unique challenges that stem cells pose to live cell imaging show how Nanolive’s new microscope, the CX-A, can overcome these difficulties
  • present never-seen-before footage of mesenchymal stem cells undergoing neural differentiation
  • discuss the dramatic phenotypic and morphological changes observed and the opportunities such research could offer

Please register here to view the webinar on-demand

Phototoxicity: The evil within

Dr. Mathieu Frechin, Head of Quantitative Biology and Hugo Moreno, Cellular Biology Engineer at Nanolive will discuss the topic of Phototoxicity in live cell imaging during our upcoming webinar on the 29th of October.

In particular, the following topics will be covered:

  • The challenge of observing live cells unperturbed
  • The effect of light exposure on living samples
  • Nanolive imaging to observe unperturbed organelle movements

Please register here to view the webinar on-demand

Automated Label-free Live Cell Imaging with the CX-A

Dr. Mathieu Frechin, Head of Quantitative Biology at Nanolive will introduce you the CX-A and its functionalities. He will outline the possibilities for parallelized experiments and image production capabilities.

In particular, the following topics will be covered:

  • Nanolive’s imaging technology
  • Presentation of the new hardware and software
  • Acquisition highlights showing data quality and new possibilities for label-free drug screening

Please register here to view the webinar on-demand

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Label-free live cell imaging meets Immuno-oncology

Dr. Mathieu Frechin, Head of Quantitative Biology at Nanolive will introduce you to our holotomographic microscopy and its implications in the field of Immuno-Oncology. During the webinar he will discuss the opportunities that are created by the usage of Nanolive’s label-free technology in the field of immune system research.

Please register here to view the webinar on-demand

Mitochondria and lipid droplets in the spotlight: Label free imaging of cell metabolism

Dr. Mathieu Frechin, Head of Quantitative Biology at Nanolive introduces you to the advantages of our holotomographic microscope for imaging key organelles supporting cellular metabolism such as mitochondria and lipid droplets. Watch how – for the first time – it is possible to image mitochondria live and completely marker free.

Please register here to view the webinar on-demand

Long-term 3D imaging and quantification of stem cell dynamics

This webinar is all about stem cell imaging with the 3D Cell Explorer. For the first time, a breakthrough in imaging stem cells has been achieved. Now it is possible to image stem cells for days, in high resolution with no need for staining or fluorescence. Dr. Mathieu Frechin, Head of Quantitative Biology at Nanolive will introduce you to Nanolive’s technology and its implications in long-term imaging of fine cellular dynamics.

Please register here to view the webinar on-demand

Understanding Nanolive label-free live cell imaging technology

The technology behind Nanolive’s microscopes is unique worldwide and is based on a fundamental patent (US 8,937,722 & EU WO 2011/121523). The combination of holography and rotational scanning makes Nanolive imaging a revolutionary technology. Holography offers a unique means to measure cells in their native environment: label-free, non-invasive, manipulation-free, and interference-free. Rotational scanning allows 3D reconstructions, noise robustness, and a resolution far beyond the accepted limit for light. To achieve optimal results for every measurement, the optics of our technology are completely self-adjusting. It guarantees the best alignment conditions – whatever the environment is.

Watch the video to understand Nanolive’s technology!

Please register here to view the video on-demand

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