Scientific Publications
Peer-reviewed research using Nanolive imagingDiscover a list of peer-reviewed scientific publications using Nanolive imaging in the fields of drug discovery, cell metabolism, etc.
Displaying 48 results:
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Impaired Glycolysis Promotes Alcohol Exposure-Induced Apoptosis in HEI-OC1 Cells via Inhibition of EGFR Signaling
Authors: Hyunsook Kang, Seong Jun Choi, Kye Hoon Park, Chi-Kyou Lee, and Jong-Seok Moon
DOI: https://doi.org/DOI: 10.3390/ijms21020476, 2020
Published in: International Journal of Molecular Sciences
Tags: Neuroscience, single cell characterization, mitochondria and cell metabolism, glycolysis, EGFR signaling, apoptosis, alcohol, HEI-OC1 cells, glucose metabolism, glucose, auditory sytem, apoptosis, hexokinase 1, HK1, AKT phosphorylation
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Autophagosome accumulation-mediated ATP energy deprivation induced by penfluridol triggers nonapoptotic cell death of lung cancer via activating unfolded protein response
Authors: Wen-Yueh Hung, Jer-Hwa Chang, Yu Cheng, Guo-Zhou Cheng, Hsiang-Ching Huang, Michael Hsiao, Chi-Li Chung, Wei-Jiunn Lee and Ming-Hsien Chien
DOI: https://doi.org/10.1038/s41419-019-1785-9, 2019
Published in: Cell Death & Disease
Tags: Drug discovery, immunooncology & oncology, mitochondria and cell metabolism, anticancer, chemotherapy, apoptosis, autophagy, drug discovery, penfluridol, lung cancer, antitumor, non-small-cell lung cancer, NSCLC, orthotopic xenograft model, viability, motility, p38
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Pleiotropic Effects of Epithelial Mesenchymal Crosstalk on Head and Neck Cancer: EMT and beyond
Authors: T. B. Steinbichler, D. Savic, D. Dejaco, A. Romani, B. Kofler, I. I. Skvortsova, H. Riechelmann, J. Dudas
DOI: https://doi.org/10.1007/s12307-019-00228-y, 2019
Published in: Cancer Microenvironment
Tags: Drug discovery, immunooncology & oncology, mitochondria and cell metabolism, epithelial mesenchymal crosstalk, EMC, tumor, tumor stroma, associated fibroblasts, cancer, head and neck cancer, chemotherapy, IL-6, JAK/STAT3/Snail signalling, radiochemotherapy, therapy resistance, conditioned medium
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Endocytosis-mediated mitochondrial transplantation: Transferring normal human astrocytic mitochondria into glioma cells rescues aerobic respiration and enhances radiosensitivity
Authors: Chao Sun, Xiongxiong Liu, Bing Wang, Zhenhua Wang, Yang Liu, Cuixia Di, Jing Si, Hongyan Li, Qingfeng Wu, Dan Xu, Ji Li, Gang Li, Yupei Wang, Fang Wang and Hong Zhang
DOI: https://dx.doi.org/10.7150%2Fthno.33100, 2019
Published in: Theranostics
Tags: Drug discovery, Immunooncology & Oncology, Mitochondria and Cell Metabolism, cellular respiration, cancer, glycolysis, mitochondria, mitochondrial dysfunction, apoptosis, radiotheraphy, resistance, glioma, endoytosis, aerobic respiration, Warburg effect, radiosensitivity, astrocytes, NAD, NADH
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Degradation of Mitochondria and Oxidative Stress as the Main Mechanism of Toxicity of Pristine Graphene on U87 Glioblastoma Cells and Tumors and HS-5 Cells
Authors: Sławomir Jaworski, Barbara Strojny, Ewa Sawosz, Mateusz Wierzbicki, Marta Grodzik, Marta Kutwin, Karolina Daniluk and André Chwalibog
DOI: https://doi.org/10.3390/ijms20030650, 2019
Published in: International Journal of Molecular Sciences
Tags: Immunooncology and Oncology, Mitochondria and cell metabolism, Neuroscience, graphene, graphene-based nanomaterials, U87 glioma cells, HS-5 cells, chicken embryo chorioallantoic membrane, pristine, ROS, mitochondrial membrane potential, oxidative stress, apoptosis, necrosis
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Label free 3D analysis of organelles in living cells by refractive index shows pre-mitotic organelle spinning in mammalian stem cells
Authors: Patrick A Sandoz, Christopher Tremblay, Sebastien Equis, Sorin Pop, Lisa Pollaro, Yann Cotte, Gisou F van der Goot, Mathieu Frechin
DOI: https://doi.org/10.1101/407239, 2018
Published in: bioRxiv
Tags: Mitochondria and cell metabolism, stem cells, epifluorescence, lipid droplets, mitochondria, endocytosis, organelle spinning
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Parvalbumin alters mitochondrial dynamics and affects cell morphology
Authors: Lucia Lichvarova, Thomas Henzi, Dzhamilja Safiulina, Allen Kaasik, Beat Schwaller
DOI: https://doi.org/10.1007/s00018-018-2921-x, 2018
Published in: Springer Nature
Tags: Mitochondria and cell metabolism, parvalbumin, pv, mitochondria, calcium, signaling, buffering, sequestration, mitochondrial morphology, mitochondrial volume, mitochondrial dynamics, fusion, fission, mitophagy
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The selexipag active metabolite ACT-333679 displays strong anti-contractile and anti- remodeling effects, but low β-arrestin recruitment and desensitization potential
Authors: Gatfield J., Menyhart K., Wanner D., Gnerre C., Monnier L., Morrison K., Hess P., Iglarz M., Clozel M. and Nayler O
DOI: https://doi.org/10.1124/jpet.116.239665, 2017
Published in: The Journal of Pharmacology and Experimental Therapeutics
Tags: Single cell characterization, drug discovery, mitochondria and cell metabolism, Prostacyclin, PGI2, receptor, pulmonary arterial hypertension, PAH, cAMP, vasoconstriction, PASMC, extracellular matrix, Selexipag, Uptravi, cell proliferation, agonism, iloprost, beraprost, treprostinil, b-arrestin, internalization, baised agonism, cardiovascular drugs, G protein coupled signaling, receptor desensitization