By using bispecific antibodies targeting a tumor-associated antigen (TAA) on the cancer cells, and CD3 on the T-cells, it is possible to redirect and activate any circulating T-cells against tumor cells independently of the specificity of their TCR. Thanks to the bridging action of such TAAxCD3 bsAb, T-cells are brought in close proximity of the target cancer cells, leading to subsequent T-cell activation and T-cell–mediated killing of the tumor cells.
For more information on T-cell redirecting κλ-bodies, please visit Light Chain Bioscience.
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We have 11 new publications featuring Nanolive imaging to round-up the end of 2022, and one to welcome 2023! Find links to all twelve papers on topics from mitochondria, to neutrophils, leukemia, red blood cells, and bacteria below.We really saw an increase in groups...
The refractive index of cellular structures is an intrinsic property that is used by Nanolive’s imaging and digital assays to analyse cells and organelles label-free. The authors of a newly published paper in Cells have innovatively applied this technology to monitor...
Upcoming Webinar – The LIVE Cell Death Assay: Drug discovery applications of cell health, stress, death, and recovery analyses
Showcasing our AI-powered digital cytotoxicity and cell viability assay, we will explore how Nanolive's high-content live cell imaging can be used to increase confidence in lead candidate selection.We will explore the following drug discovery applications of...
3D CELL EXPLORER
Budget-friendly, easy-to-use, compact solution for high quality non-invasive 4D live cell imaging
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Multimodal Complete Solution: combine high quality non-invasive 4D live cell imaging with fluorescence