By using bispecific antibodies targeting a tumor-associated antigen (TAA) on the cancer cells, and CD3 on the T-cells, it is possible to redirect and activate any circulating T-cells against tumor cells independently of the specificity of their TCR. Thanks to the bridging action of such TAAxCD3 bsAb, T-cells are brought in close proximity of the target cancer cells, leading to subsequent T-cell activation and T-cell–mediated killing of the tumor cells.
For more information on T-cell redirecting κλ-bodies, please visit Light Chain Bioscience.
Read our latest news
Nanolive is delighted to announce that you can now access the replay of our latest webinar with the topic "Maximize the biological relevance of your data whilst shortening and simplifying your experimental workflow: EVE Analytics & the CX-A".In this webinar, Dr....
Nanolive imaging suggests that cell-cell fusion could play a key role in the SARS-CoV-2 infection process
Professor Olivier Schwartz heads a 14-person strong laboratory at the Virus and Immunity lab at the prestigious Pasteur Institute in Paris. His lab studies how pathogenic viruses spread and interact with the host immune system. Before 2020, Prof. Schwartz’ research...
Table of content Introduction: characterization of single cells Background: lipid droplet dynamics 1. Quantifying LD dynamics at the population level 2. Quantifying LD dynamics at the single cell level 3. Quantifying LD dynamics at the individual LD level Conclusions...
Automated live cell imaging: a unique walk-away solution for long-term live cell imaging of single cells and cell populations
3D CELL EXPLORER-fluo
Multimodal Complete Solution: combine high quality non-invasive 4D live cell imaging with fluorescence