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  • The first versatile human iPSC‑based model of ectopic virus induction allows new insights in RNA‑virus disease

    Authors: Stefan Peischard, Huyen Tran Ho, Ilaria Piccini, Nathalie Strutz‑Seebohm, Albrecht Röpke, Ivan Liashkovich, Hiteshika Gosain, Bettina Rieger, Karin Klingel, Britta Eggers, Katrin Marcus, Wolfgang A. Linke, Frank Ulrich Müller, Stephan Ludwig, Boris Greber, Karin Busch, and Guiscard Seebohm

    https://doi.org/10.1038/s41598-020-72966-9, 2020

    Published in: Scientific Reports

    Tags: iPS-cell line; viral model system; RNA-virus expression; cardiomyocytes

  • Feature Application: Characterization of stem cells

    Authors: Nanolive SA, 2020

    Tags: Stem cells, mitosis in stem cells, stress fiber formation, stem cell differentiation

  • Specialized cytonemes induce self-organization of stem cells

    Authors: Sergi Junyent, Clare L. Garcin, James L. A. Szczerkowski, Tung-Jui Trieu, Joshua Reeves, Shukry J. Habib

    DOI: https://doi.org/10.1073/pnas.1920837117, 2020

    Published: National Academy of Sciences

    Tags: Stem cells, development, cell signaling, tissue formation, cell–cell communication, embryogenesis, Wnt

  • Molecular heterogeneity in breast carcinoma cells with increased invasive capacities

    Authors: Giulia Negro, Bertram Aschenbrenner, Simona Kranjc Brezar, Maja Cemazar, Andrej Coer, Gorana Gasljevic, Dragana Savic, Maxim Sorokin, Anton Buzdin, Maurizio Callari, Irma Kvitsaridze, Anahid Jewett, Mariela Vasileva-Slaveva, Ute Ganswindt, Prof. Ira Skvortsova, Sergej Skvortsov

    DOI: https://doi.org/10.2478/raon-2020-0007, 2020

    Published in: The Journal of Association of Radiology and Oncology

    Tags: Stem cells, Immunooncology & oncology, single cell characterization, breast cancer, metastasis, carcinoma, invasiveness, fibroblast-like, migration, stem cell, tumor growth, hormone receptor-positive, Her2-positive, triple-negative, hormone-positive, cancer stem cells, molecular profiling

  • A Gain-Of-Function RAC2 Mutation Is Associated With Bone-Marrow Hypoplasia And An Autosomal Dominant Form Of Severe Combined Immunodeficiency

    Authors: Chantal Lagresle-Peyrou, Aurélien Olichon, Hanem Sadek, Philippe Roche, Claudine Tardy, Cindy Da Silva, Alexandrine Garrigue, Alain Fischer, Despina Moshous, Yves Collette, Capucine Picard, Jean Laurent Casanova, Isabelle André, Marina Cavazzana

    DOI: https://doi.org/10.3324/haematol.2019.230250, 2020

    Published in: Haematologica

    Tags: Immunology, severe combined immunodeficiencies, SCIDs, T cells, B cells, leukopenia, RAC2 gene, p.G12R, hematopoietic stem cell transplantation, stem cell, gain of function

  • Image-based analysis of living mammalian cells using label-free 3D refractive index maps reveals new organelle dynamics and dry mass flux

    Authors: Patrick A. Sandoz, Christopher Tremblay, F. Gisou van der Goot, Mathieu Frechin 

    DOI: https://doi.org/10.1371/journal.pbio.3000553, 2019

    Published in: PLOS Biology

    Tags: Single cell characterization, stem cells, lipid droplets, mitochondria, endocytosis, endocytic structures, cell division, spinning, nuclear rotation

  • Label free 3D analysis of organelles in living cells by refractive index shows pre-mitotic organelle spinning in mammalian stem cells

    Authors: Patrick A Sandoz, Christopher Tremblay, Sebastien Equis, Sorin Pop, Lisa Pollaro, Yann Cotte, Gisou F van der Goot, Mathieu Frechin

    DOI: https://doi.org/10.1101/407239, 2018

    Published in: bioRxiv

    Tags: Mitochondria and cell metabolism, stem cells, epifluorescence, lipid droplets, mitochondria, endocytosis, organelle spinning

  • Live-stream characterization of cadmium-induced cell death using visible CdTe-QDs

    Authors: Samira Filali, Alain Geloën, Vladimir Lysenko, Fabrice Pirot & Pierre Miossec

    DOI: https://doi.org/10.1038/s41598-018-31077-2, 2018

    Published in: Scientific Reports 

    Tags: Stem cells, single cell characterization, cell death, cadmium telluride quantum dots, CdTe-QDs, mesenchymal cells, synoviocytes, apoptosis, autophagy