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Scientific Publications

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  • SARS-CoV-2 Infection Induces Psoriatic Arthritis Flares and Enthesis Resident Plasmacytoid Dendritic Cell Type-1 Interferon Inhibition by JAK Antagonism Offer Novel Spondyloarthritis Pathogenesis Insights

    Authors: Qiao Zhou; Jayakumar Vadakekolathu; Abdulla Watad; Kassem Sharif; Tobias Russell; Hannah Rowe; Almas Khan; Peter A. Millner; Peter Loughenbury; Abhay Rao; Robert Dunsmuir; Jake Timothy; Giovanni Damiani; Paolo D. M. Pigatto; Piergiorgio Malagoli; Giuseppe Banfi; Yasser M. El-Sherbiny; Cha

    https://doi.org/10.3389/fimmu.2021.635018, 2021

    Published in: Frontiers in Immunology

    Tags: plasmacytoid dendritic cells, interferon alpha, psoriatic arthritis, COVID-19, enthesis

  • Unsupervised temporal consistency improvement for microscopy video segmentation with Siamese networks

    Authors: Akhmedkhan Shabanov; Daja Schichler; Constantin Pape; Sara Cuylen-Haering; Anna Kreshuk

    https://doi.org/10.1101/2021.03.25.436993, 2021

    Published in: BioRxiv

    Tags: Segmentation; machine learning; Siamese networks

  • Comparative and Combined In Vitro Vasotoxicity of Nanoparticles Containing Lead and Cadmium

    Authors: Tatiana V. Bushueva; Ilzira A. Minigalieva; Vladimir G. Panov; Marina P. Sutunkova; Vladimir B. Gurvich; Vladimir Ya. Shur; Ekaterina V. Shishkina; Anna S. Naumova; Elizaveta P. Artemenko; Boris A. Katsnelson

    https://doi.org/10.1177/1559325820982163, 2021

    Published in: Dose-Response

    Tags: lead, cadmium, nanoparticles, cell cultures, combined toxic action

  • Variations of intracellular density during the cell cycle arise from tip-growth regulation in fission yeast

    Authors: Pascal D. Odermatt, Emrah Bostan, Kerwyn Casey Huang, Fred Chang

    https://doi.org/10.1101/2020.10.21.349696, 2020

    Published in: bioRxiv

    Tags: quantitative phase imaging; fission yeast; Schizosaccharomyces pombe; dry-mass density; cell-cycle arrest; cytokinesis; mitosis

  • Surface potential and roughness controlled cell adhesion and collagen formation in electrospun PCL fibers for bone regeneration

    Authors: Sara Metwally, Sara Ferraris, Silvia Spriano, Zuzanna J. Krysiak, Łukasz Kaniuk, Mateusz M. Marzec, Sung-Kyun Kim, Piotr K. Szewczyk, Adam Gruszczyński, Magdalena Wytrwal-Sarna, Joanna E. Karbowniczek, Andrzej Bernasik, Sohini Kar-Narayan, Urszula Stachewicz

    DOI: https://doi.org/10.1016/j.matdes.2020.108915, 2020 

    Published in: Materials & Design

    Tags: surface potential, Kelvin probe force microscopy, zeta potential, cells, adhesion, mineralization, CX-fluo, bone regeneration, interaction, morphology, fibers, osteoblast, MG63

  • Spatiotemporal changes in mechanical matrisome components of the human ovary from prepuberty to menopause

    Authors: E. Ouni, C. Bouzin, M.M. Dolmans, E. Marbaix, S. Pyr dit Ruys, D. Vertommen, C.A. Amorim

    DOI: https://doi:10.1093/humrep/deaa100, 2020

    Published in: Human Reproduction

    Tags: Ovary, extracellular matrix, hormone replacement therapy, CX, aging, fertility preservation, mechanobiology, elastic matrisome, matrisome, collagen, elastin, EMILIN-1, fiblilin-1, glycosaminoglycan, GAGs, folicle, ECM

  • Netome: The Molecular Characterization of Neutrophil Extracellular Traps (NETs)

    Authors: David Scieszka, Yi-Han Lin, Weizhong Li, Saibyasachi Choudhury, Yanbao Yu, Marcelo Freire

    DOI: https://doi.org/10.21873/anticanres.14232, 2020

    Published in: bioRxiv

    Tags: Immunology, single cell characterization, Immunology, single cell characterization, CX, HL60, HL-60, ATCC, NETs, neutrophils, extracellular DNA, genomics, proteomics, NETOME, inflammation, infection, antimicrobial

  • BA6 Induces Apoptosis via Stimulation of Reactive Oxygen Species and Inhibition of Oxidative Phosphorylation in Human Lung Cancer Cells

    Authors: Lianna Y. D’Brant, Habben Desta, Ting Chean Khoo, Anna V. Sharikova, Supriya D. Mahajan, Alexander Khmaladze

    DOI: https://doi.org/10.1117/1.JBO.24.4.046503, 2019

    Published in: Journal of Biomedical Optics

    Tags: Single cell characterization, drug discovery, neuroscience, rat, C6 glial cells, methamphetamine, Raman spectroscopy, apoptosis

  • Stimuli-sensitive fatty acid-based microparticles for the treatment of lung cancer

    Authors: Katarzyna Reczyńska, Patrycja Marchwica, Dipesh Khanal, Tomasz Borowik, Marek Langner, Elżbieta Pamuła, Wojciech Chrzanowski

    DOI: https://doi.org/10.1016/j.msec.2020.110801, 2020

    Published in: Materials and Science Engineering: C

    Tags: Immunooncology & oncology, single cell characterization, drug discovery, lung cancer, cancer therapy, superparamagnetic iron oxide nanoparticles, SPION, solid lipid microparticles, lipid, stimuli-sensitive drug carriers, anticancer drug, paclitaxel, lauric acid, LAU, myrisctic acid, palmitic acid, MYR, PAL, cell viability

  • Neutrophils are mediators of metastatic prostate cancer progression in bone

    Authors: Costanzo-Garvey, D.L., Keeley, T., Case, A.J. et al.

    DOI: https://doi.org/10.1007/s00262-020-02527-6, 2020

    Published in: Cancer Immunology, Immunotherapy

    Tags: Immunooncology & oncology, single cell characterization, neutrophils, bone, metastasis, prostate, cancer, STAT5, prostrate cancer, BM-Pca, immunotherapy, Pca, neutrophils, infiltration, apoptosis, cancer growth, cytotoxicity