Scientific Publications

Peer-reviewed research using Nanolive imaging

Discover a list of peer-reviewed scientific publications using Nanolive imaging in the fields of drug discovery, cell metabolism, etc.

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  • Research of Brain Targeting Nano Metformin on Cerebral Ischemia-Reperfusion Injury Based on Microglial Cell Activation

    Authors: Tao Tao, Sheng Guo, Hongli Zhang, Ziwei Zou, Hongjie Xi

    Published in: SSRN

    Tags: Cerebral ischemia-reperfusion injury; Apoferritin nanocages; Microglia activation; Metformin

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  • Neural crest mural cells of forebrain meninges harbor innate immune functions during early brain development and exhibit different responses to septic and toxic insults

    Authors: Sophie E Creuzet, Diego Amarante, Emmanuel Bruet, Tatiana Gorojankina

    https://doi.org/10.1101/2023.11.28.569020, 2023

    Published in: bioRxiv

    Tags: E. coli; phagocytosis, bacteria, neurons, CNC mural cells, fluorescence

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  • Co-activation of NMDAR and mGluRs controls protein nanoparticle-induced osmotic pressure in neurotoxic edema

    Authors: Zihui Zheng, Zhaoshun Qiu, Xiyu Xiong, Aobo Nie, Wenzhao Zhou, Huimin Qiu,Huanhuan Zhao, Huiwen Wu, Jun Guo

    https://doi.org/10.1016/j.biopha.2023.115917, 2023

    Published in: Biomedicine & Pharmacotherapy

    Tags: Protein nanoparticle-induced osmotic pressure;Neurotoxic edema;Glutamate receptors co-activation;Electrochemistry-tension;Enhanced sensitivity in Na+/Cl- ion channels; cell volume

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  • N-Substituted 3-Aminooxindoles and N-Propargyl Derivatives: Potential Biological Activities against Alzheimer’s Disease

    Authors: Tereza Hofmanova, Carolina Marques, Alfonso T. García-Sosa, Oscar Lopez, Luisa Leitzbach, Elisabete P. Carreiro, Aday Gonzalez-Bakker, Adrian Puerta, Holger Stark, Jose M. Padron, Jose G. Fernandez-Bolanos, Anthony J. Burke

    https://doi.org/10.1016/j.rechem.2023.101032, 2023

    Published in: Results in Chemistry

    Tags: Oxindole; Alzheimer’s disease; Cholinesterase; Mono-amine oxidase; Molecular docking; STD-NMR; Continuous live cell imaging

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  • SRF deletion results in earlier disease onset in a mouse model of amyotrophic lateral sclerosis

    Authors: Jialei Song, Natalie Yashoda Dikwella, Daniela Sinske, Francesco Roselli, and Bernd Knöll

    https://doi.org/10.1172/jci.insight.167694, 2023

    Published in: JCI Insight

    Tags: ALS; Autophagy; Mouse models; Neuroscience

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  • TXNIP contributes to induction of pro-inflammatory phenotype and caspase-3 activation in astrocytes during Alzheimer’s diseases

    Authors: Junhyung Kim, Jaejoon Lim, Ik Dong Yoo, Samel Park, Jong-Seok Moon

    https://doi.org/10.1016/j.redox.2023.102735, 2023

    Published in: Redox Biology

    Tags: Neuroscience, astrocytes, Alzheimers, cell death

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  • Interleukin-13 and its receptor are synaptic proteins involved in plasticity and neuroprotection

    Authors: Shun Li, Florian olde Heuvel, Rida Rehman, Zhenghui Li, Oumayma Aousji, Albrecht Froehlich, Wanhong Zhang, Alison Conquest, Sarah Woelfle, Michael Schoen, Caitlin O´Meara, Richard Lee Reinhardt, David Voehringer, Jan Kassubek, Albert Ludolph, Markus Huber-Lang, Bernd Knöll, Maria Cristina Morganti-Kossmann, Tobias Boeckers, Francesco Roselli

    https://doi.org/10.1038/s41467-023-35806-8, 2023

    Published in: Nature Communications

    Tags: IL-13, synapses, CREB, excitotoxicity, traumatic brain injury, nuclear pyknosis, dosing, cell death

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  • High-Resolution Spatiotemporal Analysis of Single Serotonergic Axons in an In Vitro System

    Authors: Melissa Hingorani; Adele M.L. Viviani; Jenna E. Sanfilippo; Skirmantas Janušonis

    https://doi.org/10.3389/fnins.2022.994735, 2022

    Published in: Frontiers in Neuroscience

    Tags: 5-hydroxytryptamine (5-HT), serotonergic, axon, growth cone, varicosities, development, in vitro, random walk

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  • Feature Application: Characterization of neurons

    This Feature Application shows the huge potential that Nanolive cell imaging holds for neurobiological research. Our first case study shows a timeline of the morphological changes undifferentiated primary cortical neurons undergo after exposure to neurite stimulation media. High precision segmentations are used to calculate cell metrics (e.g. volume, shape and dry mass) of interest. These calculations are directly linked to novel behaviours observed in individual neurons. Our second and third case studies focus on the sub-cellular morphological changes that stem cells undergo during neural differentiation, at both the single cell (case study 2) and population level (case study 3).

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  • Occurrence of lymphangiogenesis in peripheral nerve autografts contrasts Schwann cell-induced apoptosis of lymphatic endothelial cells in vitro

    Authors: Carina Hromada, Jaana Hartmann, Johannes Oesterreicher, Anton Stoiber, Anna Daerr, Barbara Schädl, Eleni Priglinger, Andreas H. Teuschl-Woller, Wolfgang Holnthoner, Johannes Heinzel, David Hercher

    https://doi.org/10.3390/biom12060820, 2022

    Published in: Biomolecules

    Tags: peripheral nerve regeneration, lymphangiogenesis, Schwann cells, lymphatic endothelial cells

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