Scientific Publications
Peer-reviewed research using Nanolive imagingDiscover a list of peer-reviewed scientific publications using Nanolive imaging in the fields of drug discovery, cell metabolism, etc.
Displaying 39 results:
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Abrine, an IDO1 inhibitor, suppresses the immune escape and enhances the immunotherapy of anti-PD-1 antibody in hepatocellular carcinoma
Authors: Xiaowei Liang, Hongwei Gao, Jian Xiao, Shan Han, Jia He, Renyikun Yuan, Shilin Yang and Chun Yao
https://doi.org/10.3389/fimmu.2023.1185985, 2023
Published in: Frontiers in Immunology
Tags: Immunooncology, phagocytosis, fluorescence, IDO1, Abrine, CD47, PD-L1, m6A RNA modification, immune escape, hepatocellular carcinoma, macrophages
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Fluoro-labelled sp2-iminoglycolipids with immunomodulatory properties
Authors: M. Carmen Padilla-Perez; Elena M. Sanchez-Fernandez; Aday Gonzalez-Bakker; Adrian Puerta; Jose M. Padron; Francisco Martín-Loro; Ana I. Arroba; José Manuel Garcia Fernandez; Carmen Ortiz Mellet
https://doi.org/10.1016/j.ejmech.2023.115390, 2023
Published in: European Journal of Medicinal Chemistry
Tags: Cell death, cytotoxicity, apoptosis, necrosis, EVE analytics, dry mass, cancer, oncology
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Bioengineered Bacteriophage-Like Nanoparticles as RNAi Therapeutics to Enhance Radiotherapy against Glioblastomas
Authors: Hao-Han Pang, Chiung-Yin Huang, Pin-Yuan Chen, Nan-Si Li, Ying-Pei Hsu, Jan-Kai Wu, Hsiu-Fang Fan, Kuo-Chen Wei, Hung-Wei Yang
https://doi.org/10.1021/acsnano.3c01102, 2023
Published in: ACS Nano
Tags: Glioblastoma, fluorescence, RNA silencing, gene therapy, drug discovery, endocytosis
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Multimodal study of CHI3L1 inhibition and its effect on angiogenesis, migration, immune response and refractive index of cellular structures in glioblastoma
Authors: Rusak, A., Buzalewicz, I., Mrozowska, M., Wiatrak, B., Haczkiewicz-Leśniak, K., Olbromski, M., Kmiecik, A., Krzyżak, E., Pietrowska, A., Moskal, J., Podhorska-Okołów, M., Podbielska, H., & Dzięgiel, P
https://doi.org/10.1016/j.biopha.2023.114520, 2023
Published in: Biomedicine & Pharmacotherapy
Tags: Metastasis, CHI3L1 inhibition, G721-0282, cytoskeleton, migration, actin, U-87 MG, Glioblastoma, Angiogenesis
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Interleukin-13 and its receptor are synaptic proteins involved in plasticity and neuroprotection
Authors: Shun Li, Florian olde Heuvel, Rida Rehman, Zhenghui Li, Oumayma Aousji, Albrecht Froehlich, Wanhong Zhang, Alison Conquest, Sarah Woelfle, Michael Schoen, Caitlin O´Meara, Richard Lee Reinhardt, David Voehringer, Jan Kassubek, Albert Ludolph, Markus Huber-Lang, Bernd Knöll, Maria Cristina Morganti-Kossmann, Tobias Boeckers, Francesco Roselli
https://doi.org/10.1038/s41467-023-35806-8, 2023
Published in: Nature Communications
Tags: IL-13, synapses, CREB, excitotoxicity, traumatic brain injury, nuclear pyknosis, dosing, cell death
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Antibody-modified DNase I micelles specifically recognize the neutrophil extracellular traps (NETs) and promote their degradation
Authors: Filipczak N, Li X, Saawant GR, Yalamarty SSK, Luther E, Torchilin VP
https://doi.org/10.1016/j.jconrel.2022.12.062, 2023
Published in: Journal of Controlled Release
Tags: Neutrophil extracellular traps; NETosis; Monoclonal antibody; Active targeting; 2C5; DNase I; Drug delivery system; Micelles; drug discovery
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Phenolic Fingerprinting and Bioactivity Profiling of Extracts and Isolated Compounds from Gypothamnium Pinifolium Phil.
Authors: Barrientos, R. E.; Ibáñez, E.; Puerta, A.; Padrón, J. M.; Paredes, A.; Cifuentes, F.; Romero-Parra, J.; Palacios, J.; Bórquez, J.; Simirgiotis, M. J.
https://doi.org/10.3390/antiox11122313, 2022
Published in: Antioxidants
Tags: Gypothamnium; phenolics; enzyme inhibition; native plants; antioxidant; coumarins; terpenes; hypotensive effects; HeLa; LCDA
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1,5-disubstituted-1,2,3-triazoles counteract mitochondrial dysfunction acting on F1FO-ATPase in models of cardiovascular diseases
Authors: Algieri, C.; Bernardini, C.; Marchi, S.; Forte, M.; Tallarida, M. A.; Bianchi, F.; La Mantia, D.; Algieri, V.; Stanzione, R.; Cotugno, M.; Costanzo, P.; Trombetti, F.; Maiuolo, L.; Forni, M.; De Nino, A.; Di Nonno, F.; Sciarretta, S.; Volpe, M.; Rubattu, S.; Nesci, S.
https://doi.org/10.1038/s41597-022-01798-1, 2022
Published in: Pharmacological Research
Tags: Mitochondria, metabolism, membrane potential, cardiology, cardiovascular disease, drug development
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Blockade of Platelet CysLT1R Receptor with Zafirlukast Counteracts Platelet Protumoral Action and Prevents Breast Cancer Metastasis to Bone and Lung
Authors: Lou Saier; Johnny Ribeiro; Thomas Daunizeau; Audrey Houssin; Gabriel Ichim; Caroline Barette;
Lamia Bouazza; Olivier Peyruchaudhttps://doi.org/10.3390/ijms232012221, 2022
Published in: International Journal of Molecular Sciences
Tags: platelet; metastasis; breast cancer; cysteinyl leukotrienes; CysLT1R; zafirlukast; LTRA; MGST
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Bioactive potential: a pharmacognostic definition through the screening of four Hypericum species from the Canary Islands
Authors: Rodney Lacret; Adrián Puerta; Sebastian Granica; Aday González-Bakker; Danela Hevia; Yiling Teng; Candelaria C. Sánchez-Mateo; Pedro Luis Pérez de Paz; José M. Padrón
https://doi.org/10.3390/molecules27186101, 2022
Published in: Molecules
Tags: Hypericum canariense; Hypericum glandulosum; Hypericum grandifolium; Hypericum reflexum